Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 4/20 | 0.50 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.50 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.50 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.50 |
| ▸ | CLK2 | P49760 | 3/20 | 0.50 |
| ▸ | IRAK1 | P51617 | 3/20 | 0.50 |
| ▸ | SLK | Q9H2G2 | 3/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.50 |
| ▸ | SRC | P12931 | 3/20 | 0.50 |
| ▸ | CDK1 | P06493 | 2/20 | 0.50 |
| ▸ | ROS1 | P08922 | 2/20 | 0.50 |
| ▸ | CDK2 | P24941 | 2/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.50 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.50 |
| ▸ | JAK2 | O60674 | 2/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.50 |
| ▸ | PRKACA | P17612 | 2/20 | 0.50 |
| ▸ | MARK3 | P27448 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22430336 | 0.79 | ADK (0.51) | DYRK1ADYRK3RPS6KB1CSNK1A1CSNK1D | |
| SCHEMBL22748995 | 0.79 | DYRK3 (0.51) | DYRK1ADYRK3RPS6KB1CSNK1A1CSNK1D | |
| SCHEMBL13218401 | 0.78 | SRC (0.50) | DYRK1ADYRK3RPS6KB1CSNK1A1CSNK1D | |
| SCHEMBL130592 | 0.78 | SRC (0.50) | DYRK1ADYRK3RPS6KB1CSNK1A1CSNK1D | |
| SCHEMBL15471369 | 0.74 | SRC (0.58) | RPS6KB1CSNK1A1CSNK1DCLK2SLK | |
| SCHEMBL868744 | 0.74 | PIK3CD (0.51) | DYRK1ADYRK3RPS6KB1CSNK1A1CSNK1D | |
| SCHEMBL868687 | 0.74 | ABL1 (0.58) | SRCKDRRETEGFRPIK3CG | |
| SCHEMBL21950482 | 0.74 | MAPK1 (0.60) | DYRK1ADYRK3RPS6KB1CSNK1A1CSNK1D | |
| SCHEMBL4828016 | 0.73 | SRC (0.46) | DYRK1ADYRK3RPS6KB1CSNK1A1CSNK1D | |
| SCHEMBL24096480 | 0.73 | JAK2 (0.86) | DYRK1ADYRK3RPS6KB1CSNK1A1CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113968842-B | Ibutinib intermediate compound | 鲁南制药集团股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-113968842-A | Ibrutinib intermediate compound | 鲁南制药集团股份有限公司 | 2022-01-25 | — | — | CN | disclosed |