Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.47 |
| ▸ | IDH2 | P48735 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 4/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23713159 | 0.81 | MAPT (0.44) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL11544911 | 0.75 | MPO (0.68) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL20829512 | 0.75 | MAPT (0.60) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL20385231 | 0.74 | MAPT (0.50) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL13238800 | 0.72 | MAPT (0.61) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL28978590 | 0.72 | MPO (0.67) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL21562592 | 0.72 | ALDH1A1 (0.58) | MAPTALDH1A1GAARXFP1IDH2 | |
| SCHEMBL13811262 | 0.70 | MAPK1 (0.75) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL22571349 | 0.70 | MAPT (0.43) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL7299108 | 0.70 | MAPT (0.57) | MAPTALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200291291-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200291291-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | TST, MT-ND5, MT-ND4L | MAPT 1499/4885ALDH1A1 1208/4885GAA 3319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.