Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.73 |
| ▸ | LMNA | P02545 | 5/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.73 |
| ▸ | ACACA | Q13085 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | ACP1 | P24666 | 9/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.58 |
| ▸ | RELA | Q04206 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13350452 | 0.86 | KDM4E (0.74) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL25181505 | 0.86 | ACACA (0.97) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL710469 | 0.85 | ALDH1A1 (0.66) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL951744 | 0.85 | MAPT (0.65) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL10263305 | 0.84 | KDM4E (0.73) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL29726805 | 0.84 | ACACA (1.00) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL16295684 | 0.84 | ACACA (1.00) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL25522200 | 0.84 | ACACA (1.00) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL26456461 | 0.83 | ALDH1A1 (0.64) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL6859623 | 0.83 | ALDH1A1 (0.63) | MAPTLMNAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200290977-A1 | Inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase and Uses Thereof | LA JOLLA INSTITUTE OF ALLERGY & IMMUNOLOGY | 2020-09-17 | — | — | US | disclosed |
| CN-105949118-B | A kind of preparation method of 2- aryl quinoline derivatives | 河南工业大学 | 2019-02-26 | — | — | CN | disclosed |
| CN-105949118-A | Preparation method of 2-aryl quinoline derivatives | 河南工业大学 | 2016-09-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200290977-A1 | Inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase and Uses Thereof | ACP1, PTPRCAP, PTPA | MAPT 3143/4885LMNA 3235/4885KDM4E 920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.