Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22406805 | 0.86 | AKR1C3 (0.42) | XDHMAPTHPGDALDH1A1NPC1 | |
| SCHEMBL22439736 | 0.86 | MEN1 (0.46) | SMN1; SMN2TDP1MEN1KMT2APPARA | |
| SCHEMBL22406958 | 0.85 | HPGD (0.45) | XDHMAPTHPGDALDH1A1NPC1 | |
| SCHEMBL22406867 | 0.83 | TSHR (0.46) | XDHMAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL29377336 | 0.83 | TSHR (0.46) | XDHMAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL22439711 | 0.82 | KMO (0.55) | ALDH1A1SMN1; SMN2POLBHTTKMO | |
| SCHEMBL22439730 | 0.81 | PPARA (0.45) | XDHKMOPPARA | |
| SCHEMBL22439731 | 0.80 | AKR1C2 (0.48) | AKR1C2AKR1C1DHODHTDP1SERPINE1 | |
| SCHEMBL22439737 | 0.77 | PARG (0.47) | MAPTALDH1A1NPC1RAB9ATDP1 | |
| SCHEMBL22439712 | 0.77 | SCN9A (0.44) | MAPTRAB9ASMN1; SMN2KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712135-A1 | AZOLE DERIVATIVE, INTERMEDIATE COMPOUND, METHOD FOR PRODUCING AZOLE DERIVATIVE, AGENT FOR AGRICULTURAL AND HORTICULTURAL USE, AND MATERIAL PROTECTION AGENT FOR INDUSTRIAL USE | Kureha Corporation (JP) | 2020-09-23 | — | — | EP | disclosed |