Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | PPOX | P50336 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22439717 | 0.86 | XDH (0.44) | MEN1KMT2ATDP1SMN1; SMN2PPARA | |
| SCHEMBL22439731 | 0.86 | AKR1C2 (0.48) | TDP1PPARGPPARDPPARASCN9A | |
| SCHEMBL22406829 | 0.85 | CYP11B1 (0.44) | KMT2ACYP11B1CYP11B2GSTP1TLR7 | |
| SCHEMBL22407104 | 0.84 | TLR8 (0.44) | MEN1KMT2ATTRPPOXTDP1 | |
| SCHEMBL22439730 | 0.84 | PPARA (0.45) | PPARGPPARDPPARASCN9A | |
| SCHEMBL22406867 | 0.83 | TSHR (0.46) | CYP11B1CYP11B2SMN1; SMN2PPARGPPARA | |
| SCHEMBL29377336 | 0.83 | TSHR (0.46) | CYP11B1CYP11B2SMN1; SMN2PPARGPPARA | |
| SCHEMBL22439711 | 0.82 | KMO (0.55) | FFAR1SMN1; SMN2PPARGPPARASCN9A | |
| SCHEMBL22439750 | 0.79 | PPARG (0.44) | FFAR1PPARGPPARASCN9A | |
| SCHEMBL22439712 | 0.79 | SCN9A (0.44) | CYP11B1CYP11B2SMN1; SMN2CES2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712135-A1 | AZOLE DERIVATIVE, INTERMEDIATE COMPOUND, METHOD FOR PRODUCING AZOLE DERIVATIVE, AGENT FOR AGRICULTURAL AND HORTICULTURAL USE, AND MATERIAL PROTECTION AGENT FOR INDUSTRIAL USE | Kureha Corporation (JP) | 2020-09-23 | — | — | EP | disclosed |