Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22441350 | 1.00 | CTSK (0.43) | CTSKLPAR3EPHX2TAS1R3TAS1R1 | |
| SCHEMBL31382758 | 0.88 | CTSK (0.48) | CTSKLPAR3EPHX2TAS1R3TAS1R1 | |
| SCHEMBL29365641 | 0.88 | CTSK (0.48) | CTSKLPAR3EPHX2TAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL22441261 | 0.87 | CTSK (0.45) | CTSKLPAR3EPHX2TAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL29366291 | 0.87 | CTSK (0.45) | CTSKLPAR3EPHX2TAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL22441259 | 0.87 | CTSK (0.45) | CTSKLPAR3EPHX2TAS1R3TAS1R1 | |
| SCHEMBL27175230 | 0.87 | CTSK (0.45) | CTSKLPAR3EPHX2TAS1R3TAS1R1 | |
| SCHEMBL27175226 | 0.87 | CTSK (0.45) | CTSKLPAR3EPHX2TAS1R3TAS1R1 | |
| SCHEMBL29369889 | 0.87 | ROCK2 (0.43) | CTSKLPAR3TAS1R3TAS1R1 | |
| SCHEMBL22441230 | 0.87 | ROCK2 (0.43) | CTSKLPAR3TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002280-A1 | COMPOUNDS AND METHODS OF USE | FERRO THERAPEUTICS INC (US) | 2022-01-06 | — | — | US | disclosed |
| US-11040964-B2 | Compounds and methods of use | Ferro Therapeutics, Inc. (US) | 2021-06-22 | — | — | US | disclosed |
| US-20200299283-A1 | COMPOUNDS AND METHODS OF USE | BRIDGEBIO PHARMA, INC. | 2020-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002280-A1 | COMPOUNDS AND METHODS OF USE | AIFM2, GPX4, GPX1 | CTSK 820/4885LPAR3 1473/4885EPHX2 1687/4885 |
| US-20200299283-A1 | COMPOUNDS AND METHODS OF USE | AIFM2, GPX4, GPX1 | CTSK 820/4885LPAR3 1473/4885EPHX2 1687/4885 |
| US-11040964-B2 | Compounds and methods of use | AIFM2, GPX4, GPX1 | CTSK 820/4885LPAR3 1473/4885EPHX2 1687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.