Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 8/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 8/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.36 |
| ▸ | FABP2 | P12104 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1785180 | 0.89 | PTGS2 (0.41) | PTGS2AKR1C3AKR1C2PTGS1MEN1 | |
| SCHEMBL23206105 | 0.77 | ALDH1A1 (0.35) | TSHR | |
| SCHEMBL22443155 | 0.74 | AKR1C3 (0.45) | AKR1C3AKR1C2MEN1KMT2ATSHR | |
| SCHEMBL1000705 | 0.74 | KDM4E (0.44) | PTGS2AKR1C3AKR1C2PTGS1MEN1 | |
| SCHEMBL7152622 | 0.71 | PTGS2 (0.41) | PTGS2AKR1C3AKR1C2PTGS1SLC22A6 | |
| SCHEMBL6399236 | 0.71 | PTGS2 (0.41) | PTGS2AKR1C3AKR1C2PTGS1SLC22A6 | |
| SCHEMBL7146446 | 0.71 | PTGS2 (0.41) | PTGS2AKR1C3AKR1C2PTGS1SLC22A6 | |
| SCHEMBL28915928 | 0.71 | AKR1C3 (0.40) | PTGS2AKR1C3AKR1C2PTGS1MEN1 | |
| SCHEMBL16207444 | 0.70 | PTGS1 (0.36) | PTGS2PTGS1MEN1KMT2APSEN1 | |
| SCHEMBL20993114 | 0.70 | AKR1C3 (0.42) | PTGS2AKR1C3AKR1C2PTGS1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3938347-A1 | SPECIFICALLY SUBSTITUTED 3-PHENYL-5-SPIROCYCLOPENTYL-3-PYRROLIN-2-ONES AND THEIR USE AS HERBICIDES | Bayer Aktiengesellschaft (DE) | 2022-01-19 | — | — | EP | disclosed |
| WO-2020187626-A1 | SPECIFICALLY SUBSTITUTED 3-PHENYL-5-SPIROCYCLOPENTYL-3-PYRROLIN-2-ONES AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-09-24 | — | — | WO | disclosed |