Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6305270 | 0.81 | SLC6A1 (0.34) | LTA4H | |
| SCHEMBL28167284 | 0.80 | — | — | |
| Piperazine SCHEMBL6297563 | 0.79 | DGAT1 (0.34) | NR1H2 | |
| Tert-Butyl Formate SCHEMBL27958697 | 0.78 | TDP1 (0.41) | LTA4H | |
| SCHEMBL28085952 | 0.78 | FDPS (0.41) | LTA4H | |
| Tert-Butyl Formate SCHEMBL27811987 | 0.78 | TDP1 (0.41) | LTA4H | |
| Tert-Butyl Formate SCHEMBL27811990 | 0.78 | TDP1 (0.41) | LTA4H | |
| SCHEMBL28098498 | 0.78 | SLC6A1 (0.30) | LTA4H | |
| SCHEMBL20296636 | 0.78 | SLC6A1 (0.30) | LTA4H | |
| SCHEMBL7260250 | 0.77 | CXCR4 (0.37) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020188467-A1 | CONDENSED TRICYCLIC COMPOUND USED AS KINASE INHIBITOR | 杭州英创医药科技有限公司 | 2020-09-24 | — | — | WO | disclosed |
| CN-107540692-A | Macrocyclic lactams compound containing rigid biaryl skeleton and preparation method thereof | 上海药明康德新药开发有限公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-107540691-A | Using diaryl ether as Macrocyclic lactams compound of skeleton and preparation method thereof | 上海药明康德新药开发有限公司 | 2018-01-05 | — | — | CN | disclosed |