Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22443883 | 0.81 | MERTK (0.49) | HTR7IDO1MERTKALDH1A1MAPT | |
| SCHEMBL5246257 | 0.81 | IDO1 (0.63) | HTR7IDO1XDHKMT2AMEN1 | |
| SCHEMBL22443956 | 0.77 | IDO1 (0.50) | IDO1MERTK | |
| SCHEMBL5708849 | 0.76 | ALDH1A1 (0.47) | IDO1ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL2336139 | 0.74 | HTR7 (0.56) | HTR7XDHAPPALDH1A1MAPT | |
| SCHEMBL2961408 | 0.71 | ALDH1A1 (0.65) | HTR7APPALDH1A1MAPTKMT2A | |
| SCHEMBL2955704 | 0.71 | ALDH1A1 (0.54) | HTR7XDHAPPALDH1A1MAPT | |
| SCHEMBL7250352 | 0.70 | HTR7 (0.51) | HTR7XDHAPPALDH1A1MAPT | |
| SCHEMBL27225898 | 0.70 | HTR7 (0.51) | HTR7FBP1MERTKXDHAPP | |
| SCHEMBL10134271 | 0.70 | HTR7 (0.51) | HTR7XDHAPPALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941582-A1 | SMALL MOLECULE PHOTOSENSITIZERS FOR PHOTODYNAMIC THERAPY | The University Court Of The University Of Edinburgh (GB) | 2022-01-26 | — | — | EP | disclosed |
| WO-2020187913-A1 | SMALL MOLECULE PHOTOSENSITIZERS FOR PHOTODYNAMIC THERAPY | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2020-09-24 | — | — | WO | disclosed |