Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.39 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708849 | 0.85 | ALDH1A1 (0.47) | IDO1KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL22443902 | 0.81 | HTR7 (0.48) | MERTKIDO1KMT2AMEN1ALDH1A1 | |
| SCHEMBL18896943 | 0.81 | IDO1 (0.63) | MERTKIDO1KMT2AMEN1ALDH1A1 | |
| SCHEMBL22443956 | 0.77 | IDO1 (0.50) | MERTKIDO1 | |
| SCHEMBL5708748 | 0.75 | MAPT (0.44) | KMT2AMEN1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL18988345 | 0.74 | MERTK (0.54) | MERTKKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL1298266 | 0.73 | MERTK (0.52) | MERTKKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL11060992 | 0.72 | MERTK (0.49) | MERTKKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL29901085 | 0.71 | L3MBTL1 (0.70) | MERTKKMT2AALDH1A1HTTHTR7 | |
| SCHEMBL2649297 | 0.71 | L3MBTL1 (0.70) | MERTKKMT2AALDH1A1HTTHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746094-B2 | Small molecule photosensitizers for photodynamic therapy | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2023-09-05 | — | — | US | disclosed |
| US-20220153714-A1 | SMALL MOLECULE PHOTOSENSITIZERS FOR PHOTODYNAMIC THERAPY | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2022-05-19 | — | — | US | disclosed |
| EP-3941582-A1 | SMALL MOLECULE PHOTOSENSITIZERS FOR PHOTODYNAMIC THERAPY | The University Court Of The University Of Edinburgh (GB) | 2022-01-26 | — | — | EP | disclosed |
| WO-2020187913-A1 | SMALL MOLECULE PHOTOSENSITIZERS FOR PHOTODYNAMIC THERAPY | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2020-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153714-A1 | SMALL MOLECULE PHOTOSENSITIZERS FOR PHOTODYNAMIC THERAPY | PPOX, SPR, HCCS | MERTK 1757/4885IDO1 641/4885KMT2A 1349/4885 |
| US-11746094-B2 | Small molecule photosensitizers for photodynamic therapy | PPOX, SPR, HCCS | MERTK 1923/4885IDO1 724/4885KMT2A 1140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.