Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SLC1A5 | Q15758 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10188901 | 0.87 | KDM4E (0.52) | KDM4ENPC1RAB9ABCHEGRIA2 | |
| SCHEMBL22444630 | 0.87 | KDM4E (0.52) | KDM4ENPC1RAB9ABCHEGRIA2 | |
| SCHEMBL28741491 | 0.84 | LTA4H (0.45) | NPC1RAB9ABCHEGRIK1GRIA1 | |
| SCHEMBL16147991 | 0.80 | SLC1A5 (0.58) | SLC1A5GRIK1GRIK2 | |
| SCHEMBL20899667 | 0.80 | PPARD (0.62) | KDM4ENPC1RAB9ABCHEPPARD | |
| SCHEMBL16147990 | 0.80 | SLC1A5 (0.58) | SLC1A5GRIK1GRIK2 | |
| SCHEMBL22444600 | 0.80 | SLC1A5 (0.58) | SLC1A5GRIK1GRIK2 | |
| SCHEMBL723458 | 0.79 | BCHE (0.53) | KDM4ENPC1RAB9ABCHEALDH1A1 | |
| SCHEMBL5744583 | 0.76 | PPARD (0.60) | KDM4ENPC1RAB9ABCHEALDH1A1 | |
| SCHEMBL15822888 | 0.76 | KDM4E (0.55) | KDM4ENPC1RAB9ABCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692401-A | Process for producing aromatic amino acid derivative | 中外制药株式会社 | 2021-11-23 | — | — | CN | disclosed |
| WO-2020189540-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | 中外製薬株式会社 | 2020-09-24 | — | — | WO | disclosed |