Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22448527 | 0.86 | HDAC6 (0.39) | KMT2ANPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL1200125 | 0.65 | NPC1 (0.64) | KMT2AMEN1NPC1RAB9AGSK3B | |
| SCHEMBL767242 | 0.65 | KMT2A (0.59) | KMT2AMEN1NPC1RAB9AGSK3B | |
| SCHEMBL136524 | 0.65 | ALDH1A1 (0.67) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL600578 | 0.64 | RAB9A (0.83) | KMT2AMEN1NPC1RAB9AGSK3B | |
| SCHEMBL14388863 | 0.64 | GSK3B (0.55) | KMT2AMEN1NPC1RAB9AGSK3B | |
| SCHEMBL14238637 | 0.64 | ALDH1A1 (0.60) | KMT2AMEN1NPC1RAB9AMAPT | |
| Potassium SCHEMBL30427472 | 0.63 | ALDH1A1 (0.64) | KMT2AMEN1NPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL29286645 | 0.63 | ALDH1A1 (0.64) | KMT2AMEN1NPC1RAB9AMAPT | |
| Nitrous Acid SCHEMBL27661483 | 0.62 | ALDH1A1 (0.58) | KMT2AMEN1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2877457-B1 | CYSTATHIONINE-GAMMA-LYASE (CSE) INHIBITORS | SOVA PHARMACEUTICALS INC (US) | 2020-09-23 | — | — | EP | disclosed |