Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.64 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | GALR3 | O60755 | 1/20 | 0.64 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13312947 | 1.00 | TSHR (0.64) | TSHRPMP22ADORA2AADORA3GAA | |
| SCHEMBL12157290 | 0.99 | ADORA2A (0.65) | TSHRPMP22ADORA2AADORA3GAA | |
| SCHEMBL23982425 | 0.95 | ABL1 (0.66) | PMP22GALR3NR2F2 | |
| SCHEMBL6856223 | 0.91 | ABL1 (0.62) | TSHRPMP22ADORA2AADORA3GAA | |
| SCHEMBL2041441 | 0.85 | YTHDC1 (0.59) | ADORA3 | |
| SCHEMBL29318369 | 0.85 | YTHDC1 (0.59) | ADORA3 | |
| SCHEMBL20419240 | 0.85 | ALDH1A1 (0.57) | — | |
| SCHEMBL22452057 | 0.84 | ADORA3 (0.55) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL24436940 | 0.84 | ADORA3 (0.55) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL2036287 | 0.83 | ALDH1A1 (0.55) | ADORA3NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020188288-A1 | ADENOSINE RECEPTOR AGONISTS | THE UNIVERSITY OF WARWICK (GB) | 2020-09-24 | — | — | WO | disclosed |
| CN-101392012-A | Partial and full agonists of A1 adenosine receptors | CV THERAPEUTICS INC (US) | 2009-03-25 | — | — | CN | disclosed |
| CN-1636009-A | A1Partial and full agonists of adenosine receptors | CV THERAPEUTICS INC (US) | 2005-07-06 | — | — | CN | disclosed |