Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.62 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23982425 | 0.96 | ABL1 (0.66) | ABL1RIN1PMP22 | |
| SCHEMBL13312947 | 0.91 | TSHR (0.64) | PMP22ADORA3GAAADORA2AADORA2B | |
| SCHEMBL22452225 | 0.91 | TSHR (0.64) | PMP22ADORA3GAAADORA2AADORA2B | |
| SCHEMBL12157290 | 0.90 | ADORA2A (0.65) | PMP22ADORA3GAAADORA2AADORA2B | |
| SCHEMBL5391740 | 0.83 | TSHR (0.60) | PMP22ADORA3GAAADORA2AADORA2B | |
| SCHEMBL14593728 | 0.83 | TSHR (0.60) | PMP22ADORA3GAAADORA2AADORA2B | |
| SCHEMBL2041441 | 0.83 | YTHDC1 (0.59) | ABL1RIN1ADORA3 | |
| SCHEMBL29318369 | 0.83 | YTHDC1 (0.59) | ABL1RIN1ADORA3 | |
| SCHEMBL20419240 | 0.83 | ALDH1A1 (0.57) | ABL1RIN1 | |
| SCHEMBL2036287 | 0.81 | ALDH1A1 (0.55) | ABL1RIN1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1476455-A1 | PARTIAL AND FULL AGONISTS OF A sb 1 /sb ADENOSINE RECEPTORS | CV THERAPEUTICS, INC. (US) | 2004-11-17 | — | — | EP | disclosed |
| US-6809216-B2 | WATERPROOFING, OIL REPELLENTS, ANTISOILANTS | HONEYWELL INTERNATIONAL INC. | 2004-10-26 | — | — | US | disclosed |
| US-6800788-B2 | FLUORINE-CONTAINING COMPOUNDS, AND POLYMERS DERIVED THEREFROM, FOR USE IN COMPOSITIONS USED FOR TREATING TEXTILE SUBSTRATES. ALSO PROVIDED ARE METHODS OF MAKING FLUORINE-CONTAINING COMPOUNDS AND POLYMERS DERIVED THEREFROM, COMPOSITIONS | HONEYWELL INTERNATIONAL INC. | 2004-10-05 | — | — | US | disclosed |
| WO-2003070739-A1 | PARTIAL AND FULL AGONISTS OF A1 ADENOSINE RECEPTORS | CV THERAPEUTICS, INC. (US) | 2003-08-28 | — | — | WO | disclosed |
| US-20030109626-A1 | Fluorine-containing compounds and polymers derived therefrom | HONEYWELL INTERNATIONAL INC. | 2003-06-12 | — | — | US | disclosed |
| US-20030092828-A1 | Fluorine-containing compounds and polymers derived therefrom | BRADLEY DAVID E (US) | 2003-05-15 | — | — | US | disclosed |
| US-20030039919-A1 | Fluorine-containing compounds and polymers derived therefrom | HONEYWELL INTERNATIONAL INC. | 2003-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109626-A1 | Fluorine-containing compounds and polymers derived therefrom | WASF2, NOTUM, NEFM | ABL1 231/4885RIN1 2659/4885PMP22 1544/4885 |
| US-20030092828-A1 | Fluorine-containing compounds and polymers derived therefrom | WASF2, NOTUM, PFAS | ABL1 140/4885RIN1 2389/4885PMP22 1813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.