SCHEMBL22452409

SCHEMBL22452409

NCCNCC1CCCCCCC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.47
SIGMAR1 Q99720 1/20 0.46
ADH1B P00325 1/20 0.46
ADH1C P00326 1/20 0.46
ADH1A P07327 1/20 0.46
ADH4 P08319 1/20 0.46
ADH7 P40394 1/20 0.46
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
SAT1 P21673 1/20 0.43
EPHX1 P07099 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4426094 1.00 CYP2D6 (0.47) CYP2D6SIGMAR1ADH1BADH1CADH1A
SCHEMBL22210655 1.00 CYP2D6 (0.47) CYP2D6SIGMAR1ADH1BADH1CADH1A
SCHEMBL6963827 0.98 SAT1 (0.45) CYP2D6SIGMAR1ADH1BADH1CADH1A
SCHEMBL22210659 0.96 CA12 (0.48) CYP2D6SIGMAR1ADH1BADH1CADH1A
SCHEMBL22210658 0.96 CA12 (0.48) CYP2D6SIGMAR1ADH1BADH1CADH1A
SCHEMBL22863919 0.94 SAT1 (0.53) CYP2D6SIGMAR1ADH1BADH1CADH1A
SCHEMBL4527928 0.93
SCHEMBL10936950 0.91 SIGMAR1 (0.48) CYP2D6SIGMAR1ADH1BADH1CADH1A
SCHEMBL6974114 0.91 SIGMAR1 (0.48) CYP2D6SIGMAR1ADH1BADH1CADH1A
SCHEMBL6970039 0.89 SIGMAR1 (0.52) CYP2D6SIGMAR1ADH1BADH1CADH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020191339-A1 PHOTOAFFINITY PROBES PROMEGA CORPORATION (US) 2020-09-24 WO disclosed