SCHEMBL4426094

SCHEMBL4426094

NCCNCC1CCCCC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.47
SIGMAR1 Q99720 1/20 0.46
ADH1B P00325 1/20 0.46
ADH1C P00326 1/20 0.46
ADH1A P07327 1/20 0.46
ADH4 P08319 1/20 0.46
ADH7 P40394 1/20 0.46
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
SAT1 P21673 1/20 0.43
EPHX1 P07099 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22210655 1.00 CYP2D6 (0.47) CYP2D6SIGMAR1ADH1BADH1CADH1A
SCHEMBL22452409 1.00 CYP2D6 (0.47) CYP2D6SIGMAR1ADH1BADH1CADH1A
SCHEMBL6963827 0.98 SAT1 (0.45) CYP2D6SIGMAR1ADH1BADH1CADH1A
SCHEMBL22210659 0.96 CA12 (0.48) CYP2D6SIGMAR1ADH1BADH1CADH1A
SCHEMBL22210658 0.96 CA12 (0.48) CYP2D6SIGMAR1ADH1BADH1CADH1A
SCHEMBL22863919 0.94 SAT1 (0.53) CYP2D6SIGMAR1ADH1BADH1CADH1A
SCHEMBL4527928 0.93
SCHEMBL10936950 0.91 SIGMAR1 (0.48) CYP2D6SIGMAR1ADH1BADH1CADH1A
SCHEMBL6974114 0.91 SIGMAR1 (0.48) CYP2D6SIGMAR1ADH1BADH1CADH1A
SCHEMBL6970039 0.89 SIGMAR1 (0.52) CYP2D6SIGMAR1ADH1BADH1CADH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240092964-A1 IMPREGNATION RESIN FOR A WOVEN OR STITCHED FABRIC SIKA TECHNOLOGY AG (CH) 2024-03-21 US claimed
EP-4051724-A1 IMPREGNATION RESIN FOR A WOVEN OR STITCHED FABRIC Sika Technology AG (CH) 2022-09-07 EP claimed
CN-114651096-A Impregnating resins for woven or stitched fabrics SIKA技术股份公司 2022-06-21 CN claimed
WO-2021083744-A1 IMPREGNATION RESIN FOR A WOVEN OR STITCHED FABRIC SIKA TECHNOLOGY AG (CH) 2021-05-06 WO claimed
US-12528905-B2 Amine-epoxy resin addition product SIKA TECHNOLOGY AG (CH) 2026-01-20 US disclosed
US-12516148-B2 Amine epoxy resin adduct SIKA TECHNOLOGY AG (CH) 2026-01-06 US disclosed
EP-4370580-B1 HARDENER FOR EPOXIDE RESINS SIKA TECH AG (CH) 2025-04-30 EP disclosed
US-12275817-B2 Hardener for epoxy resins SIKA TECHNOLOGY AG (CH) 2025-04-15 US disclosed
EP-4284853-B1 ADDUCT OF ALKYLATED DIAMINE AND NOVOLAK EPOXY RESIN SIKA TECH AG (CH) 2025-03-19 EP disclosed
EP-4240799-B1 SOIL PROTECTION SYSTEM WITH HIGH DYNAMIC CRACK BRIDGING SIKA TECH AG (CH) 2025-01-08 EP disclosed
US-12146024-B2 Accelerator for curing epoxy resins comprising alkylated amines SIKA TECHNOLOGY AG (CH) 2024-11-19 US disclosed
EP-4110845-B1 AMINE EPOXY RESIN ADDUCT SIKA TECH AG (CH) 2024-09-04 EP disclosed
EP-3144334-A1 HARDENER FOR LOW-EMISSION EPOXY RESIN COMPOSITIONS Sika Technology AG (CH) 2017-03-22 EP disclosed
US-20150272900-A1 Layer-By-Layer Approach to Co-Deliver DNA and siRNA via AuNPs: A Potential Platform for Modifying Release Kinetics THE JOHNS HOPKINS UNIVERSITY 2015-10-01 US disclosed
US-20140378356-A1 CYLINDER LUBRICATING OIL COMPOSITION FOR CROSSHEAD DIESEL ENGINE JX NIPPON OIL & ENERGY CORPORATION (JP) 2014-12-25 US disclosed
WO-2009067233-A1 BETA CARBOLINES AND USES THEREOF MILLENNIUM PHARMACEUTICALS, INC. (US) 2009-05-28 WO disclosed
EP-0870765-B1 AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS ZERIA PHARM CO LTD (JP) 2003-11-19 EP disclosed
US-6512000-B1 Aminocarbonyl- substituted benzimidazole derivatives for the treatment of diseases in which inhibition of tryptase is of therapeutic such as for treating an inflammatory or allergic disease BOEHRINGER INGELHEIM PHARMA KG (DE) 2003-01-28 US disclosed
US-5981557-A HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT ZERIA PHARMACEUTICAL CO., LTD. (JP) 1999-11-09 US disclosed
EP-0870765-A1 AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS ZERIA PHARMACEUTICAL CO., LTD. (JP) 1998-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150272900-A1 Layer-By-Layer Approach to Co-Deliver DNA and siRNA via AuNPs: A Potential Platform for Modifying Release Kinetics DNMT3L, DBNL, HNRNPL CYP2D6 4034/4885SIGMAR1 2648/4885ADH1B 1840/4885
US-12528905-B2 Amine-epoxy resin addition product RAD51, PTGER1, APEX1 CYP2D6 1684/4885SIGMAR1 1074/4885ADH1B 3002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.