Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA6 | P23280 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA3 | P07451 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SAT1 | P21673 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22210659 | 1.00 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL22452409 | 0.96 | CYP2D6 (0.47) | CA12CA6CA7CA9CA14 | |
| SCHEMBL22210655 | 0.96 | CYP2D6 (0.47) | CA12CA6CA7CA9CA14 | |
| SCHEMBL4426094 | 0.96 | CYP2D6 (0.47) | CA12CA6CA7CA9CA14 | |
| SCHEMBL22863919 | 0.94 | SAT1 (0.53) | CA12CA6CA7CA9CA14 | |
| SCHEMBL6963827 | 0.93 | SAT1 (0.45) | CA12CA6CA7CA9CA14 | |
| SCHEMBL4527928 | 0.89 | — | — | |
| SCHEMBL19473289 | 0.88 | SAT1 (0.52) | CA12CA6CA7CA9CA14 | |
| SCHEMBL10936950 | 0.87 | SIGMAR1 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL6974114 | 0.87 | SIGMAR1 (0.48) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820726-B2 | Motuporamine derivatives as antimicrobial agents and antibiotic enhancers against resistant gram-negative bacteria | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-11820726-B2 | Motuporamine derivatives as antimicrobial agents and antibiotic enhancers against resistant gram-negative bacteria | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-20210002206-A1 | MOTUPORAMINE DERIVATIVES AS ANTIMICROBIAL AGENTS AND ANTIBIOTIC ENHANCERS AGAINST RESISTANT GRAM-NEGATIVE BACTERIA | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2021-01-07 | — | — | US | disclosed |
| US-10710957-B2 | Motuporamine derivatives as antimicrobial agents and antibiotic enhancers against resistant gram-negative bacteria | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2020-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11820726-B2 | Motuporamine derivatives as antimicrobial agents and antibiotic enhancers against resistant gram-negative bacteria | MGAM, PGLS, NISCH | CA12 4851/4885CA6 4102/4885CA7 4347/4885 |
| US-20210002206-A1 | MOTUPORAMINE DERIVATIVES AS ANTIMICROBIAL AGENTS AND ANTIBIOTIC ENHANCERS AGAINST RESISTANT GRAM-NEGATIVE BACTERIA | MGAM, PGLS, NISCH | CA12 4851/4885CA6 4102/4885CA7 4347/4885 |
| US-10710957-B2 | Motuporamine derivatives as antimicrobial agents and antibiotic enhancers against resistant gram-negative bacteria | MGAM, PGLS, NISCH | CA12 4851/4885CA6 4102/4885CA7 4347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.