Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22452856 | 0.83 | ALDH1A1 (0.33) | CTSKCHRM2CHRM1CHRM3HPGD | |
| SCHEMBL24433847 | 0.83 | ALDH1A1 (0.33) | CTSKCHRM2CHRM1CHRM3HPGD | |
| SCHEMBL28662232 | 0.83 | ALDH1A1 (0.33) | CTSKCHRM2CHRM1CHRM3HPGD | |
| SCHEMBL17244158 | 0.82 | CTSK (0.35) | CTSKCHRM2CHRM1CHRM3HPGD | |
| SCHEMBL28674410 | 0.80 | CTSK (0.37) | CTSKCHRM2CHRM1CHRM3HPGD | |
| SCHEMBL22453424 | 0.80 | CTSK (0.37) | CTSKCHRM2CHRM1CHRM3HPGD | |
| SCHEMBL13606646 | 0.77 | NR1H2 (0.41) | CTSKCHRM2CHRM1CHRM3HPGD | |
| SCHEMBL19637550 | 0.77 | NR1H2 (0.41) | CTSKCHRM2CHRM1CHRM3HPGD | |
| SCHEMBL19959327 | 0.77 | NR1H2 (0.41) | CTSKCHRM2CHRM1CHRM3HPGD | |
| SCHEMBL21275009 | 0.75 | CHRM2 (0.36) | CTSKCHRM2CHRM1CHRM3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020188301-A1 | HETEROCYCLYL(PHENYL)METHANOL COMPOUNDS USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA | ATROGI AB (SE) | 2020-09-24 | — | — | WO | disclosed |