Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22453262 | 0.82 | CTSK (0.35) | CTSKSPHK1FPR3FPR2HPGD | |
| SCHEMBL24433847 | 0.77 | ALDH1A1 (0.33) | CTSKSPHK1HPGDCHRM2CHRM1 | |
| SCHEMBL22452856 | 0.77 | ALDH1A1 (0.33) | CTSKSPHK1HPGDCHRM2CHRM1 | |
| SCHEMBL28662232 | 0.77 | ALDH1A1 (0.33) | CTSKSPHK1HPGDCHRM2CHRM1 | |
| SCHEMBL28674410 | 0.76 | CTSK (0.37) | CTSKSPHK1HPGDCHRM2CHRM1 | |
| SCHEMBL22453424 | 0.76 | CTSK (0.37) | CTSKSPHK1HPGDCHRM2CHRM1 | |
| SCHEMBL19959327 | 0.76 | NR1H2 (0.41) | CTSKSPHK1HPGDCHRM2CHRM1 | |
| SCHEMBL20056753 | 0.76 | HSD17B10 (0.47) | FPR3FPR2HPGDALDH1A1MEN1 | |
| SCHEMBL13606646 | 0.76 | NR1H2 (0.41) | CTSKSPHK1HPGDCHRM2CHRM1 | |
| SCHEMBL19637550 | 0.76 | NR1H2 (0.41) | CTSKSPHK1HPGDCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321287-B1 | 4,5-DIHYDRO-OXAZOL-2-YL DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2015-11-11 | — | — | EP | disclosed |