Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PDE8B | O95263 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22452856 | 1.00 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2AL3MBTL1SPHK1 | |
| SCHEMBL24433847 | 1.00 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2AL3MBTL1SPHK1 | |
| SCHEMBL28658942 | 0.93 | SPHK1 (0.33) | ALDH1A1SPHK1CTSKFKBP1ATOP2A | |
| SCHEMBL24433887 | 0.93 | SPHK1 (0.33) | ALDH1A1SPHK1CTSKFKBP1ATOP2A | |
| SCHEMBL22443407 | 0.86 | FKBP1A (0.33) | FKBP1ATOP2A | |
| SCHEMBL22443492 | 0.86 | FKBP1A (0.33) | FKBP1ATOP2A | |
| SCHEMBL22443408 | 0.86 | FKBP1A (0.33) | FKBP1ATOP2A | |
| SCHEMBL22453262 | 0.83 | CTSK (0.35) | ALDH1A1MEN1KMT2ASPHK1CTSK | |
| SCHEMBL22443764 | 0.78 | FKBP1A (0.32) | FKBP1A | |
| SCHEMBL22443761 | 0.78 | FKBP1A (0.32) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113784953-A | Heterocyclyl (phenyl) carbinol compounds useful for treating hyperglycemia | 阿托基公司 | 2021-12-10 | — | — | CN | disclosed |