Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.55 |
| ▸ | CNR2 | P34972 | 4/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22452808 | 0.82 | CYP2C9 (0.48) | EPHX2MEN1KMT2A | |
| SCHEMBL22452982 | 0.82 | CYP2C9 (0.48) | EPHX2MEN1KMT2A | |
| SCHEMBL22452559 | 0.81 | CNR2 (0.43) | FAAHCNR2EPHX2POLBMEN1 | |
| SCHEMBL22453689 | 0.77 | CYP2C9 (0.44) | EPHX2MEN1KMT2A | |
| SCHEMBL22453323 | 0.76 | FAAH (0.63) | FAAHCNR2EPHX2POLBTSHR | |
| SCHEMBL22453512 | 0.76 | POLB (0.86) | FAAHCNR2EPHX2POLBTSHR | |
| SCHEMBL22453070 | 0.76 | DHODH (0.58) | FAAHCNR2EPHX2POLBTSHR | |
| SCHEMBL22452799 | 0.76 | EPHX2 (0.53) | EPHX2 | |
| SCHEMBL28355432 | 0.75 | FAAH (0.78) | FAAHCNR2EPHX2POLBTSHR | |
| SCHEMBL22452816 | 0.74 | FAAH (0.64) | FAAHCNR2EPHX2POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |