SCHEMBL22458069

SCHEMBL22458069

CCCCCCCC(CCCCCC)N1C[C@H](C)C[C@H](C)C1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EBP Q15125 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
FDPS P14324 4/20 0.35
LMNA P02545 1/20 0.34
DNM1 Q05193 1/20 0.33
GUSB P08236 2/20 0.32
OPRM1 P35372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19099370 1.00 EBP (0.36) EBPSIGMAR1FDPSLMNADNM1
SCHEMBL24555502 0.92 EBP (0.38) EBPSIGMAR1FDPSLMNADNM1
SCHEMBL20090981 0.88 ALDH1A1 (0.30)
SCHEMBL23733438 0.83 EBP (0.38) EBPSIGMAR1FDPSLMNADNM1
SCHEMBL23733443 0.83 EBP (0.38) EBPSIGMAR1FDPSLMNADNM1
SCHEMBL19055365 0.83 HRH4 (0.31)
SCHEMBL22057049 0.83 HRH4 (0.31)
SCHEMBL18625032 0.82 FDPS (0.36) EBPSIGMAR1FDPSLMNADNM1
SCHEMBL20939984 0.81 GNAI3 (0.33) EBPSIGMAR1
SCHEMBL23733448 0.81 MEN1 (0.36) EBPSIGMAR1FDPSLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219974-A1 ANTHELMINTIC AZA-BENZOTHIOPHENE AND AZA-BENZOFURAN COMPOUNDS BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2023-07-13 US disclosed
US-11560388-B2 Anthelmintic aza-benzothiophene and aza-benzofuran compounds BOEHRINGER INGELHEIM VETMEDICA GMBH 2023-01-24 US disclosed
US-20200299304-A1 ANTHELMINTIC AZA-BENZOTHIOPHENE AND AZA-BENZOFURAN COMPOUNDS BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2020-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200299304-A1 ANTHELMINTIC AZA-BENZOTHIOPHENE AND AZA-BENZOFURAN COMPOUNDS TPMT, NAT1, HNMT EBP 1058/4885SIGMAR1 4288/4885FDPS 1670/4885
US-11560388-B2 Anthelmintic aza-benzothiophene and aza-benzofuran compounds TPMT, NAT1, HNMT EBP 1058/4885SIGMAR1 4288/4885FDPS 1670/4885
US-20230219974-A1 ANTHELMINTIC AZA-BENZOTHIOPHENE AND AZA-BENZOFURAN COMPOUNDS TPMT, NAT1, HNMT EBP 1058/4885SIGMAR1 4288/4885FDPS 1670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.