SCHEMBL22458075

SCHEMBL22458075

CC(C)(S)CCOC(=O)C(C)(C)N

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21742551 0.83 GRM4 (0.37) LMNAHSD17B10
SCHEMBL16940042 0.83 LMNA (0.32) LMNAHSD17B10
SCHEMBL15679087 0.82 POLB (0.33) LMNAHSD17B10
Hydrochloric Acid SCHEMBL29006952 0.81 LMNA (0.31) LMNAHSD17B10
Hydrochloric Acid SCHEMBL29007001 0.76 LMNA (0.32) LMNAHSD17B10
SCHEMBL4696007 0.76 ALDH1A1 (0.44) LMNAHSD17B10
SCHEMBL18274690 0.76 ALDH1A1 (0.35)
SCHEMBL2302371 0.76 HCAR2 (0.39) LMNAHSD17B10
SCHEMBL15658014 0.76 TSHR (0.38) HSD17B10
SCHEMBL16641610 0.75 CYP4F2 (0.32) LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11634710-B2 Oligonucleotide compositions and methods thereof WAVE LIFE SCIENCES LTD. (SG) 2023-04-25 US disclosed
US-20200299692-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2020-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200299692-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF RBM17, HNRNPA2B1, HNRNPA1 LMNA 860/4885HSD17B10 4220/4885
US-11634710-B2 Oligonucleotide compositions and methods thereof RBM17, HNRNPA2B1, HNRNPA1 LMNA 860/4885HSD17B10 4220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.