Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983086 | 0.96 | MEN1 (0.47) | MEN1KMT2AGAATDP1CTSK | |
| SCHEMBL22460550 | 0.87 | MEN1 (0.54) | MEN1KMT2AGAATDP1CTSK | |
| SCHEMBL22460551 | 0.87 | MEN1 (0.54) | MEN1KMT2AGAATDP1CTSK | |
| SCHEMBL24573412 | 0.86 | KMT2A (0.50) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL19983115 | 0.85 | MEN1 (0.46) | MEN1KMT2AGAATDP1CTSK | |
| SCHEMBL21152479 | 0.84 | TDP1 (0.49) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL22460636 | 0.83 | MEN1 (0.44) | MEN1KMT2AGAATDP1CTSK | |
| SCHEMBL22460447 | 0.83 | MEN1 (0.44) | MEN1KMT2AGAATDP1CTSK | |
| SCHEMBL25658967 | 0.83 | TDP1 (0.47) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL22460461 | 0.81 | CTSK (0.48) | MEN1KMT2AGAATDP1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220204457-A1 | ARGININE GINGIPAIN INHIBITORS | CORTEXYME INC (US) | 2022-06-30 | — | — | US | disclosed |
| WO-2020191348-A1 | ARGININE GINGIPAIN INHIBITORS | Cortexyme, Inc. (US) | 2020-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220204457-A1 | ARGININE GINGIPAIN INHIBITORS | ARGLU1, PADI1, ARG1 | MEN1 1583/4885KMT2A 2392/4885GAA 273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.