Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | PTPRC | P08575 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1245585 | 0.73 | KDM4E (0.35) | MEN1KMT2AIDO1POLBKDM4E | |
| SCHEMBL9201732 | 0.73 | KDM4E (0.35) | MEN1KMT2AIDO1POLBKDM4E | |
| SCHEMBL3358801 | 0.72 | MAOA (0.39) | KDM4EMAPTCDC25BMAOAMAOB | |
| SCHEMBL1096641 | 0.68 | MAOA (0.36) | MEN1KMT2APOLBKDM4ELMNA | |
| SCHEMBL113314 | 0.67 | GSK3B (0.40) | MEN1KMT2AIDO1POLBKDM4E | |
| SCHEMBL29394879 | 0.67 | GSK3B (0.40) | MEN1KMT2AIDO1POLBKDM4E | |
| SCHEMBL25894 | 0.65 | — | — | |
| SCHEMBL29409540 | 0.65 | MEN1 (0.73) | MEN1KMT2AIDO1POLBKDM4E | |
| SCHEMBL2627989 | 0.65 | MEN1 (0.73) | MEN1KMT2AIDO1POLBKDM4E | |
| SCHEMBL16710160 | 0.65 | MEN1 (0.38) | MEN1KMT2AIDO1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 979 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220298174-A1 | TETRACYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI JEMINCARE PHARMACEUTICALS CO., LTD (CN) | 2022-09-22 | — | — | US | claimed |
| EP-4011886-A1 | TETRACYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) | 2022-06-15 | — | — | EP | claimed |
| EP-4006016-A2 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | CHDI Foundation, Inc. (US) | 2022-06-01 | — | — | EP | claimed |
| CN-112300195-B | Tetra-fused ring compound and preparation method and application thereof | 上海济煜医药科技有限公司 | 2021-12-24 | — | — | CN | claimed |
| US-20210198235-A1 | DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF | AURANSA INC. | 2021-07-01 | — | — | US | claimed |
| WO-2021052499-A1 | FUSED PYRIDONE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海济煜医药科技有限公司 | 2021-03-25 | — | — | WO | claimed |
| CN-112300195-A | Tetra-fused ring compound and preparation method and application thereof | 上海济煜医药科技有限公司 | 2021-02-02 | — | — | CN | claimed |
| US-20200031799-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | ATTUNE PHARMACEUTICALS, INC. | 2020-01-30 | — | — | US | claimed |
| US-20200031800-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | ATTUNE PHARMACEUTICALS, INC. | 2020-01-30 | — | — | US | claimed |
| US-20190263783-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | ATTUNE PHARMACEUTICALS, INC. | 2019-08-29 | — | — | US | claimed |
| EP-0794953-B1 | QUINAZOLINE DERIVATIVES | ZENECA LTD (GB) | 1999-05-06 | — | — | EP | claimed |
| EP-0584222-A4 | BIS MONO-AND BICYCLIC ARYL AND HETEROARYL COMPOUNDS WHICH INHIBIT EGF AND/OR PDGF RECEPTOR TYROSINE KINASE | RHONE POULENC RORER INT (US) | 1994-07-06 | — | — | EP | claimed |
| EP-0584222-A1 | BIS MONO-AND BICYCLIC ARYL AND HETEROARYL COMPOUNDS WHICH INHIBIT EGF AND/OR PDGF RECEPTOR TYROSINE KINASE. | RHONE POULENC RORER INT (US) | 1994-03-02 | — | — | EP | claimed |
| EP-0561357-A1 | Pharmaceutical composition comprising a potassium-channel-opener and an antagonist of angiotensin-II receptors | MERCK PATENT GmbH (DE) | 1993-09-22 | — | — | EP | claimed |
| WO-1992020642-A1 | BIS MONO-AND BICYCLIC ARYL AND HETEROARYL COMPOUNDS WHICH INHIBIT EGF AND/OR PDGF RECEPTOR TYROSINE KINASE | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-11-26 | — | — | WO | claimed |
| US-5114952-A | Side effect reduction | PFIZER INC. (US) | 1992-05-19 | — | — | US | claimed |
| EP-0401505-A2 | Pharmaceutical composition containing a potassium channel-activator and an ace-inhibitor | MERCK PATENT GmbH (DE) | 1990-12-12 | — | — | EP | claimed |
| EP-0346724-A1 | Chroman derivates | MERCK PATENT GmbH (DE) | 1989-12-20 | — | — | EP | claimed |
| EP-0067094-B1 | HETEROCYCLIC DERIVATIVES OF AMIDOXIMES, THEIR PREPARATION AND THERAPEUTIC USES | SYNTHELABO (FR) | 1985-10-02 | — | — | EP | claimed |
| US-4438121-A | CENTRAL NERVOUS SYSTEM DISORDER TREATMENT, ANTIDEPRESSANTS | SYNTHELABO (FR) | 1984-03-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200031800-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | KLKB1, SERPINB1, SERPINE1 | MEN1 1423/4885KMT2A 1049/4885IDO1 1136/4885 |
| US-20200031799-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | KLKB1, SERPINB1, SERPINE1 | MEN1 1423/4885KMT2A 1049/4885IDO1 1136/4885 |
| US-20190263783-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | SERPINB1, KLKB1, SERPINE1 | MEN1 2086/4885KMT2A 1381/4885IDO1 1036/4885 |
| US-20220298174-A1 | TETRACYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | KRAS, NRAS, HRAS | MEN1 204/4885KMT2A 3656/4885IDO1 4705/4885 |
| US-20210198235-A1 | DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF | THPO, PIR, PAK6 | MEN1 1394/4885KMT2A 2507/4885IDO1 1611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.