Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 5/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22462006 | 1.00 | CHRNB4 (0.48) | CHRNB4CHRNA3ALDH1A1SMN1; SMN2CHRNB2 | |
| SCHEMBL22461936 | 0.78 | SLC6A1 (0.38) | KDM4ENPC1RAB9A | |
| SCHEMBL7306648 | 0.76 | ALDH1A1 (0.44) | ALDH1A1NPC1 | |
| SCHEMBL7270911 | 0.74 | CHRNB4 (0.47) | CHRNB4CHRNA3ALDH1A1HSD17B10 | |
| SCHEMBL16902660 | 0.73 | CHRNB4 (0.47) | CHRNB4CHRNA3CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL16902659 | 0.73 | CHRNB4 (0.47) | CHRNB4CHRNA3CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL30467247 | 0.72 | CHRNB4 (0.39) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL754993 | 0.72 | CHRNB4 (0.39) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL21566378 | 0.72 | CHRNB4 (0.46) | CHRNB4CHRNA3ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL2951287 | 0.72 | NPC1 (0.53) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020191252-A1 | TECHNOLOGIES USEFUL FOR OLIGONUCLEOTIDE PREPARATION | WAVE LIFE SCIENCES LTD. (SG) | 2020-09-24 | — | — | WO | disclosed |