SCHEMBL22464

SCHEMBL22464

[CH2]Cc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.61
TSHR P16473 1/20 0.57
IDO1 P14902 3/20 0.55
CYP2C19 P33261 3/20 0.53
ALDH1A1 P00352 3/20 0.53
POLB P06746 1/20 0.53
CYP1A2 P05177 2/20 0.50
ACHE P22303 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CYP2C9 P11712 1/20 0.50
KCNJ1 P48048 1/20 0.50
KCNH2 Q12809 1/20 0.50
AKR1C3 P42330 1/20 0.48
CHRM2 P08172 1/20 0.48
PTPRF P10586 1/20 0.48
PTPN2 P17706 1/20 0.48
PTPN1 P18031 1/20 0.48
PTPN11 Q06124 1/20 0.48
LMNA P02545 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL839828 0.82 TSHR (0.64) LOXL2TSHRIDO1CYP2C19ALDH1A1
SCHEMBL971348 0.81 LOXL2 (0.61) LOXL2TSHRIDO1CYP2C19ALDH1A1
SCHEMBL44366 0.80 POLB (0.76) LOXL2TSHRIDO1CYP2C19ALDH1A1
SCHEMBL8094050 0.80 POLB (0.76) LOXL2TSHRIDO1CYP2C19ALDH1A1
SCHEMBL3292782 0.80 TSHR (0.75) LOXL2TSHRIDO1CYP2C19ALDH1A1
SCHEMBL8087428 0.80 POLB (0.76) LOXL2TSHRIDO1CYP2C19ALDH1A1
SCHEMBL8062311 0.79 IDO1 (0.70) LOXL2TSHRIDO1CYP2C19ALDH1A1
SCHEMBL22567 0.79 ALDH1A1 (0.72) LOXL2TSHRALDH1A1ACHEHSD17B10
SCHEMBL27909482 0.79 ALDH1A1 (0.72) LOXL2TSHRALDH1A1ACHEHSD17B10
SCHEMBL1119530 0.79 TSHR (0.60) LOXL2TSHRIDO1CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2665 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024127026-A1 MEMBRANE FILTRATION-ASSISTED SOLUTION PHASE OLIGONUCLEOTIDE SYNTHESIS Exactmer Limited (GB) 2024-06-20 WO claimed
CN-117264004-A Compound and nucleic acid synthesis method 深圳华大生命科学研究院 2023-12-22 CN claimed
EP-3423429-B1 MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY UNIV DE MONCTON (CA) 2023-07-12 EP claimed
US-20230014840-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND NIPPON SHINYAKU CO., LTD. (JP) 2023-01-19 US claimed
US-20230018780-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND NIPPON SHINYAKU CO., LTD. (JP) 2023-01-19 US claimed
CN-115093448-A Nitrogen-antimony octylene alkyl antimony derivatives and synthesis method thereof 湖南大学 2022-09-23 CN claimed
CN-114981281-A Method for producing oligonucleotide compound 日本新药株式会社 2022-08-30 CN claimed
CN-114981280-A Method for producing oligonucleotide compound 日本新药株式会社 2022-08-30 CN claimed
WO-2022123501-A1 PROTECTED DEOXYDIDEHYDRO-NUCLEOSIDES VICTORIA LINK LIMITED (NZ) 2022-06-16 WO claimed
CN-114206389-A Multivalent ligand clusters for targeted delivery of therapeutic agents 有丝分裂疗法有限责任公司 2022-03-18 CN claimed
WO-1988000201-A1 NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES CALIFORNIA INSTITUTE OF TECHNOLOGY, INC. (US) 1988-01-14 WO claimed
EP-0239354-A2 2,2-Dinitrophenylethane derivatives and their application as protecting compounds Wendstone Chemicals P.L.C. (GB) 1987-09-30 EP claimed
US-4689411-A ANTIBIOTICS OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) 1987-08-25 US claimed
US-4603014-A Thiazolinoazetidinone derivatives and process for the preparation of the same OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) 1986-07-29 US claimed
EP-0079740-B1 ANTHRANILOYLOXYALKANOATES RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) 1985-11-13 EP claimed
US-4521537-A ANALGESICS HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1985-06-04 US claimed
EP-0064796-B1 PHOSPHORYLATING AGENT AND PROCESS FOR THE PHOSPHORYLATION OF ORGANIC HYDROXYL COMPOUNDS UNILEVER N.V. (NL) 1985-05-15 EP claimed
US-4482561-A ANALGESICS, ANTIINFLAMMATORY AGENT, ANTICOAGULANT, AND ANTIDEPRESSANT RECORDATI, S. A., CHEMICAL & PHARMACEUTICAL CO. (CH) 1984-11-13 US claimed
EP-0102034-A1 Spiro(2H-1,4-benzodioxepin-3(5H)4'-piperidine and 3'-pyrrolidino) compounds, a process for preparing the same and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1984-03-07 EP claimed
EP-0079740-A1 Anthraniloyloxyalkanoates RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) 1983-05-25 EP claimed