Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.69 |
| ▸ | SHBG | P04278 | 7/20 | 0.51 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.43 |
| ▸ | PGR | P06401 | 4/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7112542 | 1.00 | AR (0.69) | ARSHBGSLC22A1ALDH1A1SERPINA6 | |
| SCHEMBL12355430 | 1.00 | AR (0.69) | ARSHBGSLC22A1ALDH1A1SERPINA6 | |
| SCHEMBL6012294 | 1.00 | AR (0.69) | ARSHBGSLC22A1ALDH1A1SERPINA6 | |
| SCHEMBL6012356 | 1.00 | AR (0.69) | ARSHBGSLC22A1ALDH1A1SERPINA6 | |
| SCHEMBL24103283 | 1.00 | AR (0.69) | ARSHBGSLC22A1ALDH1A1SERPINA6 | |
| SCHEMBL12364347 | 1.00 | AR (0.69) | ARSHBGSLC22A1ALDH1A1SERPINA6 | |
| SCHEMBL24102490 | 1.00 | AR (0.69) | ARSHBGSLC22A1ALDH1A1SERPINA6 | |
| SCHEMBL24102641 | 1.00 | AR (0.69) | ARSHBGSLC22A1ALDH1A1SERPINA6 | |
| SCHEMBL24103277 | 1.00 | AR (0.69) | ARSHBGSLC22A1ALDH1A1SERPINA6 | |
| SCHEMBL30339913 | 1.00 | AR (0.69) | ARSHBGSLC22A1ALDH1A1SERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042352-B1 | ANDROGENIC STEROID COMPOUNDS AND A METHOD OF MAKING AND USING THE SAME | RES TRIANGLE INST (US) | 2007-07-25 | — | — | EP | claimed |
| EP-1272196-B1 | METHODS OF MAKING THE 4-N-BUTYLCYCLOHEXANOIC AND THE UNDECANOIC ACID ESTERS OF (7 ALPHA,11 BETA)-DIMETHYL-17 BETA-HYDROXY-4-ESTREN-3-ONE AND THEIR MEDICAL USE | US GOV HEALTH & HUMAN SERV (US) | 2006-08-02 | — | — | EP | claimed |
| US-20040097477-A1 | Androgenic steroid compounds and a method of making and using the same | RESEARCH TRIANGLE INSTITUTE (US) | 2004-05-20 | — | — | US | claimed |
| US-20030069215-A1 | Methods of making and using 7a,11b-dimethyl-17b-hydroxy-4-estren-3-one 17b-trans-4-n-butylcyclohexane carboxylate and 7a,11b-dimethyl-17b-hydroxyestr-4-en-3-one 17-undecanoate | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, | 2003-04-10 | — | — | US | claimed |
| US-20020103177-A1 | Androgenic steroid compounds and a method of making and using the same | COOK C EDGAR (US) | 2002-08-01 | — | — | US | claimed |
| US-6369047-B2 | ESTR-4-EN-3-ONE DERIVATIVES WITH ENHANCED ACTIVITY RELATIVE TO TESTOSTERONE DUE TO ENHANCED POTENCY; REDUCTION IN SIZE OF SKIN PATCHES | RESEARCH TRIANGLE INSTITUTE | 2002-04-09 | — | — | US | claimed |
| US-20020002156-A1 | ANDROGENIC STEROID COMPOUNDS AND A METHOD OF MAKING AND USING THE SAME | COOK C EDGAR (US) | 2002-01-03 | — | — | US | claimed |
| US-5952319-A | CONTROLLING MALE FERTILITY IN MAMMAL | RESEARCH TRIANGLE INSTITUTE (US) | 1999-09-14 | — | — | US | claimed |
| US-20250281509-A1 | SEQUENTIAL HORMONE THERAPY TO IMPROVE SURVIVAL AND ENHANCE RESPONSE TO IMMUNE THERAPY IN MEN WITH PROSTATE CANCER | THE JOHNS HOPKINS UNIVERSTY | 2025-09-11 | — | — | US | disclosed |
| EP-3782649-B1 | BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS | ASCENDIS PHARMA AS (DK) | 2025-05-14 | — | — | EP | disclosed |
| US-20250041316-A1 | METHODS AND COMPOSITIONS FOR TREATING LIVER DISEASE | UNIV TEMPLE (US) | 2025-02-06 | — | — | US | disclosed |
| US-20250026818-A1 | MALE CONTRACEPTION | Sciencemed Spóka z ograniczon odpowiedzialnoci (PL) | 2025-01-23 | — | — | US | disclosed |
| EP-4419122-A1 | MALE CONTRACEPTION | SCIENCEMED SPÓLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (PL) | 2024-08-28 | — | — | EP | disclosed |
| US-20230381323-A1 | RELEASABLE CONJUGATES | FISH & RICHARDSON PC | 2023-11-30 | — | — | US | disclosed |
| US-20020103177-A1 | Androgenic steroid compounds and a method of making and using the same | COOK C EDGAR (US) | 2002-08-01 | — | — | US | disclosed |
| WO-2001074839-A3 | METHODS OF MAKING THE 4-N-BUTYLCYCLOHEXANOIC AND THE UNDECANOIC ACID ESTERS OF (7 ALPHA, 11 BETA)-DIMETHYL-17 BETA-HYDROXY-4-ESTREN-3-ONE AND THEIR MEDICAL USE | US GOV HEALTH & HUMAN SERV (US) | 2002-06-13 | — | — | WO | disclosed |
| US-6369047-B2 | ESTR-4-EN-3-ONE DERIVATIVES WITH ENHANCED ACTIVITY RELATIVE TO TESTOSTERONE DUE TO ENHANCED POTENCY; REDUCTION IN SIZE OF SKIN PATCHES | RESEARCH TRIANGLE INSTITUTE | 2002-04-09 | — | — | US | disclosed |
| US-20020002156-A1 | ANDROGENIC STEROID COMPOUNDS AND A METHOD OF MAKING AND USING THE SAME | COOK C EDGAR (US) | 2002-01-03 | — | — | US | disclosed |
| WO-2001074839-A2 | METHODS OF MAKING THE 4-N-BUTYLCYCLOHEXANOIC AND THE UNDECANOIC ACID ESTERS OF (7 ALPHA, 11 BETA)-DIMETHYL-17 BETA-HYDROXY-4-ESTREN-3-ONE AND THEIR MEDICAL USE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2001-10-11 | — | — | WO | disclosed |
| US-5952319-A | CONTROLLING MALE FERTILITY IN MAMMAL | RESEARCH TRIANGLE INSTITUTE (US) | 1999-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020002156-A1 | ANDROGENIC STEROID COMPOUNDS AND A METHOD OF MAKING AND USING THE SAME | NR5A1, CYP17A1, SHBG | AR 4/4885SHBG 3/4885SLC22A1 1907/4885 |
| US-20040097477-A1 | Androgenic steroid compounds and a method of making and using the same | NR5A1, CYP17A1, SHBG | AR 4/4885SHBG 3/4885SLC22A1 1907/4885 |
| US-20230381323-A1 | RELEASABLE CONJUGATES | GUSB, ABCB11, UGT2B7 | AR 2336/4885SHBG 472/4885SLC22A1 796/4885 |
| US-20250041316-A1 | METHODS AND COMPOSITIONS FOR TREATING LIVER DISEASE | LIPC, GYS2, FABP1 | AR 250/4885SHBG 5/4885SLC22A1 891/4885 |
| US-20020103177-A1 | Androgenic steroid compounds and a method of making and using the same | NR5A1, CYP17A1, SHBG | AR 4/4885SHBG 3/4885SLC22A1 1907/4885 |
| US-20030069215-A1 | Methods of making and using 7a,11b-dimethyl-17b-hydroxy-4-estren-3-one 17b-trans-4-n-butylcyclohexane carboxylate and 7a,11b-dimethyl-17b-hydroxyestr-4-en-3-one 17-undecanoate | HSD17B11, CYP19A1, SHBG | AR 197/4885SHBG 3/4885SLC22A1 1535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.