SCHEMBL27797228

SCHEMBL27797228

O=C(Cl)Oc1ccc(OOC(=O)c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 1/20 0.53
▸ LMNA P02545 1/20 0.53
▸ PARP10 Q53GL7 1/20 0.53
▸ KMT2A Q03164 11/20 0.50
▸ MAPT P10636 4/20 0.50
▸ TDP1 Q9NUW8 3/20 0.50
▸ ALDH1A1 P00352 3/20 0.50
▸ L3MBTL1 Q9Y468 1/20 0.50
▸ PKM P14618 1/20 0.50
▸ MEN1 O00255 3/20 0.49
▸ RAB9A P51151 1/20 0.47
▸ HSD17B10 Q99714 2/20 0.43
▸ TSHR P16473 2/20 0.43
▸ ELANE P08246 1/20 0.43
▸ CASP3 P42574 1/20 0.43
▸ SENP7 Q9BQF6 1/20 0.43
▸ KDM4E B2RXH2 1/20 0.42
▸ GAA P10253 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10560176 0.87 F2 (0.70) F2LMNAPARP10KMT2AMAPT
SCHEMBL5244678 0.83 F2 (0.70) F2LMNAPARP10KMT2AMAPT
SCHEMBL22468182 0.82 F2 (0.57) F2LMNAPARP10KMT2AMAPT
SCHEMBL28051725 0.80 F2 (0.59) F2LMNAPARP10KMT2AMAPT
SCHEMBL10560170 0.80 LMNA (0.59) F2LMNAPARP10KMT2AMAPT
SCHEMBL725405 0.79 PARP10 (0.77) F2LMNAPARP10KMT2AMAPT
SCHEMBL20599493 0.79 LMNA (0.57) F2LMNAPARP10KMT2AMAPT
SCHEMBL94313 0.79 F2 (0.57) F2LMNAPARP10KMT2AMAPT
SCHEMBL29221160 0.79 F2 (0.57) F2LMNAPARP10KMT2AMAPT
SCHEMBL27684899 0.79 LMNA (0.57) F2LMNAPARP10KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101874048-A Polyethylene copolymer BOREALIS TECH OY 2010-10-27 — — CN disclosed
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