Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | MARK3 | P27448 | 1/20 | 0.48 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.48 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.48 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.48 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146186 | 0.86 | SCN9A (0.44) | KMT2AMEN1L3MBTL1PIM1MARK3 | |
| SCHEMBL5871186 | 0.84 | L3MBTL1 (0.51) | KMT2AMEN1L3MBTL1PIM1MARK3 | |
| SCHEMBL145542 | 0.82 | PTGS1 (0.45) | KMT2AMEN1KDM4EALDH1A1HTT | |
| SCHEMBL29651126 | 0.80 | KMT2A (0.76) | KMT2AMEN1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL1746797 | 0.80 | KMT2A (0.76) | KMT2AMEN1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL30620463 | 0.78 | L3MBTL1 (0.50) | KMT2AMEN1L3MBTL1PIM1MARK3 | |
| SCHEMBL27257521 | 0.78 | L3MBTL1 (0.53) | KMT2AMEN1L3MBTL1PIM1MARK3 | |
| SCHEMBL23883832 | 0.78 | LMNA (0.43) | KMT2AMEN1L3MBTL1ALDH1A1ACHE | |
| SCHEMBL30719630 | 0.78 | L3MBTL1 (0.53) | KMT2AMEN1L3MBTL1PIM1MARK3 | |
| SCHEMBL23496956 | 0.78 | L3MBTL1 (0.53) | KMT2AMEN1L3MBTL1PIM1MARK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113631548-B | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2023-06-06 | — | — | CN | disclosed |
| EP-3947360-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | Zoetis Services LLC (US) | 2022-02-09 | — | — | EP | disclosed |
| CN-113631548-A | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2021-11-09 | — | — | CN | disclosed |
| WO-2020198478-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2020-10-01 | — | — | WO | disclosed |