SCHEMBL22470560

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9578959	0.84	CA2 (0.50)	AKR1B1LMNAMAPTHTTCA2
	SCHEMBL8142964	0.84	CA2 (0.50)	AKR1B1LMNAMAPTHTTCA2
	SCHEMBL15200857	0.80	AKR1B1 (0.50)	AKR1B1LMNAMAPTHTTCA2
	SCHEMBL28304649	0.73	KDM4E (0.41)	AKR1B1LMNAMAPTHTTCA2
	SCHEMBL896933	0.72	RAPGEF4 (0.56)	LMNACA2RAPGEF4CA1MMP1
	SCHEMBL250285	0.72	CA2 (0.62)	AKR1B1LMNAMAPTHTTCA2
	SCHEMBL2122562	0.72	CA2 (0.62)	AKR1B1LMNAMAPTHTTCA2
	SCHEMBL18187419	0.72	CA2 (0.62)	AKR1B1LMNAMAPTHTTCA2
	SCHEMBL8978700	0.72	CA2 (0.62)	AKR1B1LMNAMAPTHTTCA2
	SCHEMBL23988486	0.71	AKR1B1 (0.39)	AKR1B1LMNAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.