SCHEMBL896933

SCHEMBL896933

O=S(=O)(c1ccc(I)cc1)c1ccc(I)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.56
CA1 P00915 6/20 0.54
CA2 P00918 6/20 0.54
MMP1 P03956 1/20 0.54
MMP2 P08253 1/20 0.54
MMP9 P14780 1/20 0.54
MMP8 P22894 1/20 0.54
MMP13 P45452 1/20 0.54
CYP3A4 P08684 2/20 0.52
HTR6 P50406 2/20 0.52
ALDH1A1 P00352 1/20 0.52
MAPK1 P28482 1/20 0.52
LMNA P02545 1/20 0.52
MPO P05164 1/20 0.52
CYP2C9 P11712 1/20 0.52
TSHR P16473 1/20 0.52
GAA P10253 1/20 0.52
F2 P00734 2/20 0.48
PRSS1 P07477 2/20 0.48
PRSS2 P07478 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9676951 0.92 RAPGEF4 (0.50) RAPGEF4CA1CA2MMP1MMP2
SCHEMBL3835169 0.89 HTR6 (0.70) RAPGEF4CA1CA2MMP1MMP2
SCHEMBL13291387 0.87 HSD11B1 (0.47) RAPGEF4CA1CA2MMP1MMP2
SCHEMBL8142964 0.87 CA2 (0.50) RAPGEF4CA1CA2MMP1MMP2
SCHEMBL8149854 0.87 ALDH1A1 (0.76) RAPGEF4CA1CA2MMP1MMP2
SCHEMBL12755316 0.87 GAA (0.76) RAPGEF4CA1CA2MMP1MMP2
SCHEMBL14060649 0.87 GAA (0.55) RAPGEF4CA1CA2MMP1MMP2
SCHEMBL9578959 0.87 CA2 (0.50) RAPGEF4CA1CA2MMP1MMP2
SCHEMBL3669592 0.85 HTT (0.55) RAPGEF4CA1CA2MMP1MMP2
SCHEMBL10379037 0.83 RAPGEF4 (0.48) RAPGEF4CA1CA2MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114479063-B Polyarylether nitrile containing naphthalene structure and preparation method and application thereof 中国石油化工股份有限公司 2024-06-28 CN claimed
US-5576417-A Method for synthesizing aromatic polymers DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1996-11-19 US claimed
EP-0502993-B1 PROCESS FOR THE PREPARATION OF COPOLY(ARYLENE SULFIDE) HAVING A DECREASED AMOUNT OF DISULFIDE RADICALS EASTMAN CHEM CO (US) 1995-06-07 EP claimed
EP-0530707-A1 Method for preparing polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP claimed
EP-0530705-A1 Method for producing polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP claimed
EP-0530703-A2 Method for the preparation of polyamide-imides EASTMAN KODAK COMPANY (US) 1993-03-10 EP claimed
EP-0522469-A2 Preparation of poly(benz(ox, imid, thi)azole) polymers EASTMAN KODAK COMPANY (US) 1993-01-13 EP claimed
US-5179193-A From dihaloaromatic sulfone, polyhalodiarylsulfone and polymerizable sulfur source; coatings, films, moldings, fibers PHILLIPS PETROLEUM COMPANY (US) 1993-01-12 US claimed
US-5177174-A Branched aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1993-01-05 US claimed
WO-1992018556-A1 PROCESS FOR THE PREPARATION OF COPOLY(ARYLENE SULFIDE) HAVING AN ENHANCED RATE OF CRYSTALLIZATION EASTMAN KODAK COMPANY (US) 1992-10-29 WO claimed
US-5155183-A Heating with iodine-terminated polyphenylene sulfide in melt p hase EASTMAN KODAK COMPANY (US) 1992-10-13 US claimed
US-5149755-A Aroatmic amine and halide reactants EASTMAN KODAK COMPANY (US) 1992-09-22 US claimed
EP-0502993-A1 PROCESS FOR THE PREPARATION OF COPOLY(ARYLENE SULFIDE) HAVING A DECREASED AMOUNT OF DISULFIDE RADICALS. EASTMAN KODAK CO (US) 1992-09-16 EP claimed
US-5104971-A In non-ortho position with solvent and catalyst under pressure EASTMAN KODAK COMPANY (US) 1992-04-14 US claimed
EP-0459386-A1 Preparation of polyamides EASTMAN KODAK COMPANY (US) 1991-12-04 EP claimed
WO-1991009072-A1 PROCESS FOR THE PREPARATION OF COPOLY(ARYLENE SULFIDE) HAVING AN INCREASED AMOUNT OF DISULFIDE RADICALS EASTMAN KODAK COMPANY (US) 1991-06-27 WO claimed
WO-1991008249-A1 PROCESS FOR THE PREPARATION OF COPOLY(ARYLENE SULFIDE) HAVING A DECREASED AMOUNT OF DISULFIDE RADICALS EASTMAN KODAK COMPANY (US) 1991-06-13 WO claimed
US-4977224-A Process for the preparation of copoly(arylene sulfide) having a decreased amount of disulfide radicals EASTMAN KODAK COMPANY (US) 1990-12-11 US claimed
WO-1990013589-A1 PROCESS FOR THE PREPARATION OF LOW COLOR COPOLY(ARYLENE SULFIDE) EASTMAN KODAK COMPANY (US) 1990-11-15 WO claimed
US-4945155-A Preparation of low color copoly(arylene sulfide) by heating copoly(arylene sulfide) EASTMAN KODAK COMPANY (US) 1990-07-31 US claimed