SCHEMBL22472391

SCHEMBL22472391

Cc1ccc2c(oc3nc4nccnc4n32)c1-c1ccc(-c2c(-c3ccccc3)c(-c3ccccc3)c(-c3ccccc3)c(-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAT2A P31153 2/20 0.33
NPC1 O15118 3/20 0.32
RAB9A P51151 2/20 0.32
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
BACE1 P56817 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
KMT2A Q03164 1/20 0.31
MDM2 Q00987 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30
ADORA2A P29274 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22472473 0.94 MAT2A (0.32) MAT2ANPC1RAB9AKMT2A
SCHEMBL22472385 0.78 ADORA2A (0.40) NPC1RAB9AMAPTSMN1; SMN2NPSR1
SCHEMBL22472452 0.72 KDM4E (0.40) NPC1RAB9AMAPTSMN1; SMN2NPSR1
SCHEMBL22472368 0.69 NPC1 (0.47) NPC1RAB9AMAPTNPSR1KMT2A
SCHEMBL22472519 0.68 BACE1 (0.36) BACE1KMT2A
SCHEMBL22472520 0.66 NPY5R (0.31)
SCHEMBL22472394 0.66 NPC1 (0.42) NPC1RAB9AMAPTSMN1; SMN2NPSR1
SCHEMBL22472521 0.64 TNK2 (0.31) SMN1; SMN2NFKB1NFKB2RELAALDH1A1
SCHEMBL22472388 0.64 KDM4E (0.34) NPC1RAB9AMAPTSMN1; SMN2NPSR1
SCHEMBL9611675 0.60 ADORA2A (0.50) NPC1RAB9ABACE1KMT2AADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10790455-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10790455-B2 Organic electroluminescent materials and devices ORC3, ALKBH2, ENPP3 MAT2A 2473/4885NPC1 4454/4885RAB9A 2730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.