SCHEMBL22472472

SCHEMBL22472472

Cc1ccc2c(nc3oc4ccccc4n32)c1-c1ccc(-c2c(-c3ccccc3)cc(-c3ccccc3)c(-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.38
RAB9A P51151 2/20 0.38
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
CASP3 P42574 2/20 0.32
SENP8 Q96LD8 2/20 0.32
SENP7 Q9BQF6 2/20 0.32
SENP6 Q9GZR1 2/20 0.32
MAOB P27338 1/20 0.31
ALDH1A1 P00352 3/20 0.31
MAPT P10636 2/20 0.31
BLM P54132 1/20 0.31
NCOA1 Q15788 1/20 0.31
NCOA3 Q9Y6Q9 1/20 0.31
ENPP3 O14638 1/20 0.30
ENPP1 P22413 1/20 0.30
NUDT1 P36639 1/20 0.30
GAA P10253 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22472394 0.93 NPC1 (0.42) NPC1RAB9AMEN1KMT2ACASP3
SCHEMBL22472469 0.81
SCHEMBL22472521 0.73 TNK2 (0.31) ALDH1A1KDM4EHPGDSMN1; SMN2
SCHEMBL22472452 0.73 KDM4E (0.40) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL22100054 0.72 NPC1 (0.47) NPC1RAB9AKMT2ACASP3SENP8
SCHEMBL22472473 0.70 MAT2A (0.32) NPC1RAB9AMEN1KMT2ANUDT1
SCHEMBL22472385 0.69 ADORA2A (0.40) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL20893122 0.67 NPC1 (0.50) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL22472390 0.67 RAB9A (0.42) NPC1RAB9AKMT2AALDH1A1MAPT
SCHEMBL17507363 0.67 NPC1 (0.54) NPC1RAB9AKMT2ACASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10790455-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10790455-B2 Organic electroluminescent materials and devices ORC3, ALKBH2, ENPP3 NPC1 4454/4885RAB9A 2730/4885MEN1 2333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.