Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1753618 | 0.82 | MT-CO2 (0.33) | MT-CO2ALOX5 | |
| SCHEMBL20228114 | 0.82 | MT-CO2 (0.33) | MT-CO2ALOX5 | |
| SCHEMBL23839856 | 0.78 | MT-CO2 (0.31) | MT-CO2ALOX5 | |
| SCHEMBL20215129 | 0.78 | MT-CO2 (0.31) | MT-CO2ALOX5 | |
| SCHEMBL19360073 | 0.77 | PIK3CD (0.38) | PIK3CD | |
| SCHEMBL21984606 | 0.77 | ADAM17 (0.35) | PIK3CD | |
| SCHEMBL14962670 | 0.74 | MAPT (0.39) | MT-CO2ALOX5 | |
| SCHEMBL19134327 | 0.74 | ALDH1A1 (0.30) | — | |
| SCHEMBL22472710 | 0.73 | LMNA (0.44) | PIK3CD | |
| SCHEMBL15498412 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787480-B2 | Cytotoxic peptides and conjugates thereof | NOVARTIS AG (CH) | 2020-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787480-B2 | Cytotoxic peptides and conjugates thereof | CD47, NGLY1, VIP | PIK3CD 2987/4885MT-CO2 4608/4885ALOX5 4056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.