SCHEMBL2247284

SCHEMBL2247284

CCCCN(CCCC)Cc1cccc(C)c1O

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EGFR P00533 7/20 0.58
MAPT P10636 2/20 0.47
BCHE P06276 2/20 0.44
ACHE P22303 2/20 0.44
ALDH1A1 P00352 1/20 0.42
ERBB2 P04626 4/20 0.41
DRD2 P14416 1/20 0.40
OPRM1 P35372 1/20 0.40
DRD3 P35462 1/20 0.40
OPRD1 P41143 1/20 0.40
OPRK1 P41145 1/20 0.40
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 1/20 0.40
TRPA1 O75762 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11278702 0.90 GABRA1 (0.48) EGFRMAPTBCHEACHEERBB2
SCHEMBL20175927 0.84 MAPT (0.56) EGFRMAPTBCHEACHEALDH1A1
SCHEMBL11263143 0.83 DRD2 (0.47) EGFRBCHEACHEDRD2OPRM1
SCHEMBL29601849 0.82 MAPT (0.62) EGFRMAPTBCHEACHE
SCHEMBL15641887 0.79 BCHE (0.43) EGFRMAPTBCHEACHE
SCHEMBL11257150 0.78 EGFR (0.44) EGFRMAPTBCHEACHEALDH1A1
SCHEMBL11278959 0.78 GABRA1 (0.52) MAPTBCHEALDH1A1DRD2OPRM1
SCHEMBL11797948 0.78 MAPT (0.52) MAPTBCHEACHE
SCHEMBL10486437 0.77 HTR1A (0.56) MAPTBCHEACHEDRD2OPRM1
SCHEMBL29558088 0.77 ALOX5 (0.54) EGFRALDH1A1TRPA1GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4004080-B1 POLY(ARYLENE ETHER) COMPOSITIONS SHPP GLOBAL TECH BV (NL) 2023-08-16 EP disclosed
EP-3612583-B1 POLY(PHENYLENE ETHER) COPOLYMER PROCESS AND COMPOSITIONS SHPP GLOBAL TECH BV (NL) 2023-01-18 EP disclosed
US-20220259369-A1 POLY(ARYLENE ETHER) COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2022-08-18 US disclosed
US-11111336-B2 Poly(phenylene ether) copolymer process and compositions SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2021-09-07 US disclosed
US-11041046-B2 Method for poly(phenylene ether) manufacture and associated poly(phenylene ether) SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2021-06-22 US disclosed
WO-2021022156-A1 POLY(ARYLENE ETHER) COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-02-04 WO disclosed
US-20200385519-A1 PROCESS FOR THE MANUFACTURE OF THERMOSETTING POLY(ARYLENE ETHER) COPOLYMER AND COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2020-12-10 US disclosed
US-20200199297-A1 POLY(PHENYLENE ETHER) COPOLYMER PROCESS AND COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2020-06-25 US disclosed
EP-3514195-B1 DUAL FUNCTIONAL POLY(ARYLENE ETHER) COMPOUNDS SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-05-27 EP disclosed
US-10662288-B2 Dual functional poly(arylene ether) compounds SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-05-26 US disclosed
US-20190225748-A1 DUAL FUNCTIONAL POLY(ARYLENE ETHER) COMPOUNDS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-07-25 US disclosed
EP-3514195-A1 DUAL FUNCTIONAL POLY(ARYLENE ETHER) COMPOUNDS SABIC Global Technologies B.V. (NL) 2019-07-24 EP disclosed
EP-2841487-B1 POLY(PHENYLENE ETHER) COPOLYMER AND METHOD OF MAKING SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-04-25 EP disclosed
US-20180079863-A1 METHOD FOR POLY(PHENYLENE ETHER) MANUFACTURE AND ASSOCIATED POLY(PHENYLENE ETHER) SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2018-03-22 US disclosed
EP-2297247-B1 POLY(ARYLENE ETHER)-POLYSILOXANE COMPOSITION AND METHOD SABIC INNOVATIVE PLASTICS IP (NL) 2016-03-09 EP disclosed
US-8017697-B2 Poly(arylene ether)-polysiloxane composition and method SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-09-13 US disclosed
US-20110190453-A1 POLY(ARYLENE ETHER)-POLYSILOXANE COMPOSITION AND METHOD SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2011-08-04 US disclosed
US-20110190454-A1 POLY(ARYLENE ETHER)-POLYSILOXANE COMPOSITION AND METHOD SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2011-08-04 US disclosed
US-20090318635-A1 POLY(ARYLENE ETHER)-POLYSILOXANE COMPOSITION AND METHOD SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-12-24 US disclosed