Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.40 |
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960272 | 0.81 | MEN1 (0.44) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL21251507 | 0.75 | MAPT (0.40) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL22473611 | 0.73 | MEN1 (0.44) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL13669995 | 0.73 | MEN1 (0.41) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28045393 | 0.70 | MEN1 (0.41) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6979719 | 0.70 | MEN1 (0.47) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9515353 | 0.70 | MEN1 (0.47) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL12667811 | 0.70 | MEN1 (0.47) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL18648260 | 0.69 | NOS3 (0.36) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL13879231 | 0.69 | MEN1 (0.53) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787448-B2 | Indolizino [3,2-C] quinoline-based fluorescent probe | SEOUL NATIONAL UNIVERSITY R & DB FOUNDATION (KR) | 2020-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787448-B2 | Indolizino [3,2-C] quinoline-based fluorescent probe | DNA2, IRF3, DDB1 | MEN1 3101/4885KMT2A 3767/4885MAPT 1031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.