SCHEMBL22474491

SCHEMBL22474491

C=C(Cc1cccc(C)c1)C(=O)OCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTBP2 P56545 1/20 0.48
POLB P06746 1/20 0.47
KMT2A Q03164 2/20 0.45
ALDH1A1 P00352 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
HPGD P15428 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.43
MAOB P27338 2/20 0.41
TP53 P04637 1/20 0.41
IDO1 P14902 2/20 0.41
NPC1 O15118 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
MMP12 P39900 1/20 0.41
CES2 O00748 1/20 0.40
ACHE P22303 1/20 0.40
CES1 P23141 1/20 0.40
KCNQ2 O43526 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5426625 0.85 EGFR (0.44) ALDH1A1L3MBTL1MAPTMAOB
SCHEMBL25400177 0.85 MAPT (0.47) KMT2AALDH1A1L3MBTL1MEN1MAPT
SCHEMBL10544357 0.85 XPO1 (0.52) CTBP2KMT2AALDH1A1HPGDSMN1; SMN2
SCHEMBL7637134 0.84 CTBP2 (0.50) CTBP2POLBKMT2AALDH1A1L3MBTL1
SCHEMBL29846895 0.84 CTBP2 (0.51) CTBP2POLBKMT2AALDH1A1L3MBTL1
SCHEMBL7341455 0.84 CTBP2 (0.51) CTBP2POLBKMT2AALDH1A1L3MBTL1
SCHEMBL394740 0.83 ALDH1A1 (0.56) KMT2AALDH1A1L3MBTL1SMN1; SMN2MEN1
SCHEMBL9133136 0.81 MAPT (0.51) POLBKMT2AALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL25398808 0.81 XPO1 (0.55) POLBKMT2AALDH1A1HPGDSMN1; SMN2
SCHEMBL1107143 0.80 KMT2A (0.56) CTBP2POLBKMT2AALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570675-B2 Boronic acid compounds LG CHEM, LTD. (KR) 2026-03-10 US disclosed
US-20240101579-A1 BORONIC ACID COMPOUNDS LG CHEM, LTD. (KR) 2024-03-28 US disclosed
EP-4242213-A1 BORONIC ACID COMPOUND Lg Chem, Ltd. (KR) 2023-09-13 EP disclosed
CN-116568310-A Boric acid compounds 株式会社LG化学 2023-08-08 CN disclosed
WO-2022123530-A1 BORONIC ACID COMPOUND 주식회사 엘지화학 2022-06-16 WO disclosed
EP-2876108-B1 COMPOUNDS OF CHIRAL AROMATIC SPIROKETAL DIPHOSPHINE LIGANDS, PREPARATION METHODS AND USES THEREOF SHANGHAI INST ORGANIC CHEMISTRY CAS (CN) 2020-09-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570675-B2 Boronic acid compounds PSMB6, PSMB3, PSMB2 CTBP2 300/4885POLB 2583/4885KMT2A 2072/4885
US-20240101579-A1 BORONIC ACID COMPOUNDS PSMB11, PSMB1, BACH1 CTBP2 677/4885POLB 2634/4885KMT2A 1197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.