Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MBOAT4 | Q96T53 | 4/20 | 0.36 |
| ▸ | TKT | P29401 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22475338 | 0.81 | MBOAT4 (0.36) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL22475306 | 0.81 | MBOAT4 (0.39) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL24251660 | 0.74 | L3MBTL1 (0.42) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL17490419 | 0.74 | MAPT (0.42) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL21756757 | 0.74 | ALDH1A1 (0.42) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL29392742 | 0.74 | L3MBTL1 (0.42) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL21756758 | 0.70 | ALDH1A1 (0.41) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL11441604 | 0.67 | SCN9A (0.50) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL16931357 | 0.66 | MAP4K4 (0.49) | ALDH1A1L3MBTL1KDM4EHSD17B10 | |
| SCHEMBL22475329 | 0.66 | HRH3 (0.49) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210009613-A1 | ARYLPHOSPHINE OXIDES FOR INHIBITING KINASE ACTIVITY | SHENZHEN TARGETRX, INC. (CN) | 2021-01-14 | — | — | US | disclosed |
| EP-3715350-A1 | ARYLPHOSPHINE OXIDES FOR INHIBITING KINASE ACTIVITY | Shenzhen TargetRx, Inc. (CN) | 2020-09-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009613-A1 | ARYLPHOSPHINE OXIDES FOR INHIBITING KINASE ACTIVITY | ALK, SKP1, ROS1 | ALDH1A1 1138/4885MAPT 3200/4885L3MBTL1 1240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.