Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | HPGD | P15428 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18294603 | 0.81 | HPGD (0.48) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL18294602 | 0.75 | TUBB4A (0.56) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL8980474 | 0.71 | ALDH1A1 (0.72) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL312265 | 0.71 | SMN1; SMN2 (0.74) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL312000 | 0.67 | HPGD (0.61) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL18294607 | 0.67 | HPGD (0.50) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL6295964 | 0.66 | ALDH1A1 (0.81) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL1181656 | 0.66 | BCHE (0.50) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL8980242 | 0.66 | PDE10A (0.76) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL9385766 | 0.65 | HPGD (0.68) | ALDH1A1HPGDKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3302488-B1 | NOVEL USE OF ARYL-QUINOLIN DERIVATIVES AS INHIBITORS OF VASCULOGENIC MIMICRY | TAIRX INC (TW) | 2020-09-30 | — | — | EP | disclosed |