Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.73 |
| ▸ | HPGD | P15428 | 9/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.73 |
| ▸ | LMNA | P02545 | 6/20 | 0.73 |
| ▸ | MEN1 | O00255 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | CTSV | O60911 | 1/20 | 0.61 |
| ▸ | CTSL | P07711 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311823 | 0.88 | KDM4E (0.74) | SMN1; SMN2ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL312000 | 0.87 | HPGD (0.61) | SMN1; SMN2ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL6534299 | 0.84 | HPGD (1.00) | SMN1; SMN2ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL312025 | 0.83 | KDM4E (0.51) | SMN1; SMN2ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL6295964 | 0.80 | ALDH1A1 (0.81) | SMN1; SMN2ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL311524 | 0.80 | CTSV (0.75) | SMN1; SMN2ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL311852 | 0.80 | KDM4E (0.51) | SMN1; SMN2ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL31552890 | 0.80 | KDM4E (0.51) | SMN1; SMN2ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL25910968 | 0.78 | KDM4E (0.55) | SMN1; SMN2ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL339089 | 0.78 | RAB9A (0.55) | SMN1; SMN2ALDH1A1HPGDKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242130-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-08-14 | — | — | US | disclosed |
| EP-1838296-B1 | FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | RESVERLOGIX CORP (CA) | 2012-08-08 | — | — | EP | disclosed |
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |
| US-20090259048-A1 | FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | RESVERLOGIX CORP. (CA) | 2009-10-15 | — | — | US | disclosed |
| US-20060205767-A1 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | HEPALINK (HONG KONG) LIMITED (HK) | 2006-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205767-A1 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | APOB, APOL1, FABP3 | SMN1; SMN2 2736/4885ALDH1A1 1211/4885HPGD 138/4885 |
| US-20090259048-A1 | FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | APOB, APOL1, FABP3 | SMN1; SMN2 2736/4885ALDH1A1 1211/4885HPGD 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.