Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | IL2RA | P01589 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | IL2 | P60568 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25949990 | 0.88 | ACE (0.46) | ACEGAAALDH1A1THRBCYP2C9 | |
| SCHEMBL23154537 | 0.88 | ACE (0.46) | ACEGAAALDH1A1THRBCYP2C9 | |
| SCHEMBL18688556 | 0.88 | ACE (0.46) | ACEGAAALDH1A1THRBCYP2C9 | |
| SCHEMBL22476506 | 0.87 | ACE (0.41) | ACEOPRM1OPRD1OPRK1GAA | |
| SCHEMBL21699258 | 0.87 | CYP2C9 (0.49) | GAAATML3MBTL1ALDH1A1THRB | |
| SCHEMBL21699268 | 0.87 | CYP2C9 (0.49) | GAAATML3MBTL1ALDH1A1THRB | |
| SCHEMBL19443278 | 0.86 | MMP1 (0.44) | ACEGAAMMP1ALDH1A1THRB | |
| SCHEMBL22476544 | 0.86 | MMP1 (0.44) | ACEMMP1 | |
| SCHEMBL18683750 | 0.84 | NPC1 (0.41) | GAAATML3MBTL1ALDH1A1 | |
| SCHEMBL22476529 | 0.83 | L3MBTL1 (0.45) | ACEGAAMMP1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303366-B1 | DERIVATIVES OF DOLASTATIN 10 AND USES THEREOF | NEWBIO THERAPEUTICS INC (CN) | 2020-09-30 | — | — | EP | disclosed |