Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.40 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24006345 | 0.78 | HDAC1 (0.45) | HDAC1HDAC3HDAC2NCOR1HDAC8 | |
| SCHEMBL8943196 | 0.78 | HDAC1 (0.49) | HDAC1HDAC3HDAC2NCOR1HDAC8 | |
| SCHEMBL19980897 | 0.76 | HDAC1 (0.40) | HDAC1HDAC3HDAC2ALDH1A1HSD17B10 | |
| SCHEMBL8379952 | 0.75 | HDAC1 (0.47) | HDAC1HDAC3HDAC2MAPTKDM4E | |
| SCHEMBL6075087 | 0.75 | S100B (0.51) | HDAC1HDAC3HDAC2MAPTALDH1A1 | |
| SCHEMBL19980976 | 0.74 | HDAC1 (0.41) | HDAC1HDAC3HDAC2 | |
| SCHEMBL22476585 | 0.74 | HDAC1 (0.41) | HDAC1HDAC3HDAC2MAPTNPSR1 | |
| SCHEMBL22212876 | 0.74 | HDAC1 (0.46) | HDAC1HDAC3HDAC2 | |
| SCHEMBL15244180 | 0.73 | HDAC1 (0.45) | HDAC1HDAC3HDAC2MAPTKDM4E | |
| SCHEMBL19980985 | 0.71 | HDAC1 (0.38) | HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3715423-A1 | HIGH WET FAST DISPERSE DYE MIXTURES OF N-[4-(5-FLUORO-2,4-DINITRO-PHENYLAZO)-PHENYL]-AMINE DERIVATIVES AND N-[4-(4-NITRO-PHENYLAZO)-PHENYL]-AMINE DERIVATIVES | DyStar Colours Distribution GmbH (DE) | 2020-09-30 | — | — | EP | disclosed |