Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980976 | 0.96 | HDAC1 (0.41) | HDAC1HDAC2HDAC3TSHR | |
| SCHEMBL19981012 | 0.90 | HDAC1 (0.33) | HDAC1HDAC2BTKTSHRPTGER4 | |
| SCHEMBL22212876 | 0.90 | HDAC1 (0.46) | HDAC1HDAC2HDAC3TSHRPTGER4 | |
| SCHEMBL19980987 | 0.89 | MTNR1B (0.35) | HDAC1HDAC2HDAC3PTGER4 | |
| SCHEMBL19980897 | 0.81 | HDAC1 (0.40) | HDAC1HDAC2HDAC3BTKTSHR | |
| SCHEMBL19980954 | 0.80 | PHLPP2 (0.40) | BTKTSHR | |
| SCHEMBL19980979 | 0.79 | S100B (0.48) | TSHR | |
| SCHEMBL19980998 | 0.79 | POLB (0.30) | — | |
| SCHEMBL19903994 | 0.77 | TSHR (0.35) | HDAC1HDAC2HDAC3TSHR | |
| SCHEMBL24006345 | 0.77 | HDAC1 (0.45) | HDAC1HDAC2HDAC3LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |