Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21384154 | 0.81 | GABRP (0.39) | GPR52CYP11B1CYP11B2DAO | |
| SCHEMBL29442862 | 0.81 | GABRP (0.39) | GPR52CYP11B1CYP11B2DAO | |
| SCHEMBL755263 | 0.78 | GRM2 (0.42) | CYP11B1CYP11B2LMNAMEN1KMT2A | |
| SCHEMBL21395199 | 0.78 | TAAR1 (0.45) | LMNAKDM4E | |
| SCHEMBL21394846 | 0.78 | TAAR1 (0.45) | CYP11B1CYP11B2SMN1; SMN2P2RX7KDM4E | |
| SCHEMBL12885845 | 0.77 | KCNQ3 (0.43) | CYP11B1CYP11B2SMN1; SMN2GAATSHR | |
| SCHEMBL21395212 | 0.77 | P4HTM (0.49) | GPR52DAOLMNAMEN1KMT2A | |
| SCHEMBL21384012 | 0.76 | PARP1 (0.45) | GPR52MEN1KMT2AKDM4E | |
| Lithium Ion SCHEMBL21384056 | 0.75 | SNCA (0.40) | GPR52DAOP2RX7 | |
| SCHEMBL28671700 | 0.71 | GPR52 (0.33) | GPR52DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |