SCHEMBL755263

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18836883	0.83	TSHR (0.41)	MEN1KMT2AGAATSHRSMN1; SMN2
	SCHEMBL1564270	0.82	PLA2G7 (0.50)	GAATSHRSMN1; SMN2CYP11B1CYP11B2
	SCHEMBL753107	0.82	GRM2 (0.41)	GRM2MEN1KMT2AHTTTAAR1
	SCHEMBL21394846	0.80	TAAR1 (0.45)	TAAR1SMN1; SMN2CYP11B1CYP11B2
	SCHEMBL24167640	0.80	CYP3A4 (0.56)	MEN1KMT2AGAATSHRSMN1; SMN2
	SCHEMBL15920609	0.80	TSHR (0.39)	MEN1KMT2AGAATSHRSMN1; SMN2
	SCHEMBL18459203	0.80	CYP11B1 (0.54)	TSHRSMN1; SMN2ALDH1A1MAPTHPGD
	SCHEMBL1772749	0.80	EPHX2 (0.43)	MEN1KMT2ATAAR1GAATSHR
	SCHEMBL29887750	0.80	CYP3A4 (0.56)	MEN1KMT2AGAATSHRSMN1; SMN2
	SCHEMBL15920652	0.80	TSHR (0.42)	MEN1KMT2AGAATSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.