Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13545685 | 0.84 | FFAR2 (0.46) | FFAR2NR3C1ALDH1A1TRPM8SMN1; SMN2 | |
| SCHEMBL2936251 | 0.82 | FFAR2 (0.49) | FFAR2NR3C1ALDH1A1GSK3BTRPM8 | |
| SCHEMBL9942595 | 0.81 | FFAR2 (0.44) | FFAR2NR3C1ALDH1A1TRPM8SMN1; SMN2 | |
| SCHEMBL972961 | 0.80 | FFAR2 (0.43) | FFAR2NR3C1ALDH1A1TRPM8SMN1; SMN2 | |
| SCHEMBL18969622 | 0.80 | FFAR2 (0.43) | FFAR2NR3C1ALDH1A1TRPM8PKM | |
| SCHEMBL30088848 | 0.79 | ALDH1A1 (0.43) | FFAR2NR3C1ALDH1A1TRPM8SMN1; SMN2 | |
| SCHEMBL14591145 | 0.78 | FFAR2 (0.49) | FFAR2NR3C1ALDH1A1TRPM8SMN1; SMN2 | |
| SCHEMBL13359498 | 0.77 | FFAR2 (0.48) | FFAR2NR3C1ALDH1A1TRPM8SMN1; SMN2 | |
| SCHEMBL13585397 | 0.75 | FFAR2 (0.42) | FFAR2NR3C1ALDH1A1TRPM8PKM | |
| SCHEMBL27872396 | 0.75 | FFAR2 (0.42) | FFAR2NR3C1ALDH1A1TRPM8PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332459-B2 | Benzimidazole derivatives and their uses | TEIJIN PHARMA LIMITED (JP) | 2022-05-17 | — | — | US | disclosed |
| US-20200308145-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USES | AMGEN INC. (US) | 2020-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308145-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USES | TRPC6, TRPV6, TRPM6 | FFAR2 923/4885NR3C1 4187/4885ALDH1A1 1564/4885 |
| US-11332459-B2 | Benzimidazole derivatives and their uses | TRPC6, TRPV6, TRPM6 | FFAR2 923/4885NR3C1 4187/4885ALDH1A1 1564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.