Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 2/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11954378 | 0.77 | POLB (0.36) | POLBALDH1A1MAPTALOX15RECQL | |
| SCHEMBL24334703 | 0.75 | GRIA1 (0.56) | EPHX1 | |
| SCHEMBL3043384 | 0.74 | POLB (0.44) | POLBALDH1A1MAPTALOX15RECQL | |
| SCHEMBL2835677 | 0.74 | POLB (0.34) | POLBEPHX1 | |
| SCHEMBL9631930 | 0.73 | PNMT (0.33) | PNMT | |
| SCHEMBL22757767 | 0.73 | POLB (0.34) | POLBALDH1A1MAPTALOX15RECQL | |
| SCHEMBL12707759 | 0.73 | POLB (0.34) | POLBALDH1A1MAPTALOX15RECQL | |
| Potassium Ion SCHEMBL9631915 | 0.73 | PNMT (0.33) | PNMT | |
| SCHEMBL9953138 | 0.73 | ALDH1A1 (0.41) | POLBALDH1A1MAPTALOX15RECQL | |
| SCHEMBL12789674 | 0.73 | EPHX1 (0.55) | POLBALDH1A1MAPTEPHX1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198583-A1 | BICYCLIC JAK INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2020-10-01 | — | — | WO | disclosed |