Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22483005 | 0.91 | TP53 (0.34) | TP53THRBPOLBL3MBTL1MTNR1A | |
| SCHEMBL22483038 | 0.79 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL22483004 | 0.76 | GAA (0.47) | POLBALDH1A1NPSR1 | |
| SCHEMBL13413721 | 0.71 | CASP2 (0.50) | CASP2THRBPOLBL3MBTL1MTNR1A | |
| SCHEMBL9772333 | 0.62 | TSHR (0.48) | CASP2TP53MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL22521716 | 0.61 | TOP2A (0.41) | ALDH1A1 | |
| SCHEMBL7537764 | 0.59 | CASP2 (0.86) | CASP2 | |
| SCHEMBL16120761 | 0.59 | PTGS1 (0.46) | CASP2MTNR1AMTNR1BALDH1A1TSHR | |
| SCHEMBL2633147 | 0.58 | CASP2 (0.70) | CASP2ALDH1A1 | |
| SCHEMBL13413716 | 0.58 | MEN1 (0.52) | TP53THRBPOLBL3MBTL1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020192665-A1 | NUCLEOSIDE DERIVATIVE FOR PREVENTING AND TREATING INFLAMMATION AND APPLICATION THEREOF | 四川大学华西医院 | 2020-10-01 | — | — | WO | disclosed |