Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22483009 | 0.91 | CASP2 (0.35) | TP53TSHRMTNR1AMTNR1BPOLB | |
| SCHEMBL22483038 | 0.81 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL22483004 | 0.80 | GAA (0.47) | MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL13413716 | 0.69 | MEN1 (0.52) | TP53TSHRMEN1KMT2AMTNR1A | |
| SCHEMBL22521716 | 0.60 | TOP2A (0.41) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9877458 | 0.59 | TP53 (0.61) | TP53TSHRMEN1KMT2AMTNR1A | |
| SCHEMBL13413721 | 0.57 | CASP2 (0.50) | TSHRMTNR1AMTNR1BPOLBTHRB | |
| SCHEMBL19375505 | 0.57 | PDE4A (0.33) | ALDH1A1 | |
| SCHEMBL24777174 | 0.56 | MTNR1A (0.56) | TP53TSHRMEN1KMT2AMTNR1A | |
| SCHEMBL15235369 | 0.56 | MTNR1A (0.53) | TP53TSHRMEN1KMT2AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020192665-A1 | NUCLEOSIDE DERIVATIVE FOR PREVENTING AND TREATING INFLAMMATION AND APPLICATION THEREOF | 四川大学华西医院 | 2020-10-01 | — | — | WO | disclosed |